Endometrial cancer is classified into four molecular subtypes of which the p53 abnormal variant is biologically aggressive. Programmed cell death protein 1 (PD-1) is a cell surface receptor and a vital inhibitor of the immune response. Programmed death ligand 1 (PD-L1) is a trans-membrane co-...
参考文献: Jamieson, Amy et al. “Clinical Behavior and Molecular Landscape of Stage I p53-abnormal Low-Grade Endometrioid Endometrial Carcinomas.”Clinical cancer research : an official journal of the American Association ...
参考文献: Jamieson, Amy et al. “Clinical Behavior and Molecular Landscape of Stage I p53-abnormal Low-Grade Endometrioid Endometrial Carcinomas.”Clinical cancer research : an official journal of the American Association for Cancer Research, 10.1158/1078-0432.CCR-23-1397. 29 Sep. 2023,doi:10.115...
“Clinical Behavior and Molecular Landscape of Stage I p53-abnormal Low-Grade Endometrioid Endometrial Carcinomas.”Clinical cancer research : an official journal of the American Association for Cancer Research, 10.1158/1078-0432.CCR-23-1397. 29 Sep. 2023,doi:10.1158/1078-0432.CCR-23-1397发布于 2...
Jamieson, Amy et al. “Clinical Behavior and Molecular Landscape of Stage I p53-abnormal Low-Grade Endometrioid Endometrial Carcinomas.”Clinical cancer research : an official journal of the American Association for Cancer Research, 10.1158/1078-0432.CCR-23-1397. 29 Sep. 2023,doi:10.1158/1078-043...
Ayhan A, Tuncer ZS, Ruacan S, Yasui W, Tahara E (1998) Abnormal expression of cripto and p53 protein in endometrial carcinoma and its precursor lesions. Eur J Gynaecol Oncol 19:316–318 PubMed CAS Google Scholar Bakalkin G, Selivanova G, Yakovleva T, Kiseleva E, Kashuba E, Magnusson...
张杰-聊城:@廖芝玲_广西肿瘤医院 是的,临床治疗一样,往浆液报更安全!不用纠结。 廖芝玲_广西肿瘤医院:好,我觉得这是集二者于一体的癌 掌心0164@汪俊:@廖芝玲_广西肿瘤医院 看看您这个病例符合不符合p53阳性的子宫内膜样腺癌? 掌心0164@汪俊: D EFI...
their respective target proteins. In addition, lncRNAs can target other RNAs and metabolites, consequently interfering with gene expression. Like miRNAs, there has been a multitude of studies linking the dysregulation of lncRNAs to cancer. Thus, it was repeatedly shown that abnormal expression of ...
wtp53 promotes death of cells that form these structures, whereas mutp53 contributes to formation of cell-in-cell structures in lung adenocarcinoma through live cell engulfment, leading to abnormal mitosis [72]. Thus, the crosstalk between mutp53 and genome instability is critical to cancer devel...
This approach has enabled the integration of IHC as a standard diagnostic marker for the “p53 abnormal” molecular subtype in endometrial cancer, which is associated with high-risk disease [5]. However, the clinical significance of immunohistochemical pattern analysis of p53 expression in BC remains...