Find out more about the organ-on-a-chip models, their advantages and future developments in our Topic of the Month.
Products for Organoid and Organ-on-a-chip Imaging 3D image stack of an angiogenesis model cultured using the OrganoPlate® system (MIMETAS). Nikon’s recently introduced AX / AX R series of confocal microscopes are applicable toward 3D cell culture imaging. The usability of the AX / AX R ...
Cartilage tissue engineering is complex owing to the apt choice of biopolymers, cell source and dynamic simulation. Herein, we elucidate a novel approach to mesenchymal stem cells (MSCs)- induced chondrogenesis using microfluidics on an organ-on-a-chip (
It is commonly used to precisely control microfluidic (10−9 to 10−18 L) fluids using channels that range in size from tens to hundreds of microns and is known as a “lab-on-a-chip” [1,2,3,4]. The microchannel is small, but has a large surface area and high mass transfer,...
In the past few years, the emergence of organoids and organ-on-a-chip (OOAC) technologies, which are complementary to animal models and two-dimensional cell culture methods and can better simulate the internal environment of the human body, provides a new platform for traditional Chinese medicin...
Most of the materials used to create organ-on-a-chip devices need to be optically clear for viewing and imaging purposes, although whether they are stiff or flexible depends on the use of the device. The materials must also have the right chemistry and reactivity so as to not improperly aff...
Introduction: Organ-on-a-chip (OC) platforms have demonstrated the importance of architectural arrangement in in vitro platforms. A common practice in most OC systems is the use of customized polydimethylsiloxane (PDMS) structures, which allow for the construction of fluidic systems in which cells ...
(TOKYO, JAPAN) will sequentially start to provide “Organ-on-a-Chip Imaging and Analysis contract services.” Beginning June 1, 2022, services will be offered at Nikon BioImaging Labs where each company operates to support drug discovery research using cells. In the drug discovery field, cells...
Microfluidic organ-on-chip systems for periodontal research: advances and future directions Authors: Gopu Sriram, Hardik Makkar Roadblocks confronting widespread dissemination and deployment of Organs on Chips Authors: Charles G. Alver, Emma Drabbe, Matthew Ishahak … Shining a light on Candida -ind...
Development of a functional glomerulus at the organ level on a chip to mimic hypertensive nephropathy. Sci. Rep. 6, 31771 (2016). Article Google Scholar Mastikhina, O. et al. Human cardiac fibrosis-on-a-chip model recapitulates disease hallmarks and can serve as a platform for drug ...