Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4. Proc Natl Acad Sci USA 94: 9562-9567, 1997.Zhang D, Sliwkowski MX, Mark M, et al. Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4. Proc Natl Acad...
目的探讨氯胺酮连续给药致小鼠产生的类似精神分裂症症状,与精神分裂症易感基因神经调节蛋白1(neuregulin-1,NRG1)及其受体ErbB4 mRNA表达的相关性,为研究精神分裂症的可能发病机制提供参考依据。方法50只雄性昆明种小鼠,随机分为生理盐水组、氯胺酮小剂量(25 mg/kg)、中剂量(50 mg/kg)、大剂量(100 mg/kg)组和氯...
PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling. The international journal of biochemistry & cell biol- ogy. 2015; 61:53-62. doi: 10.1016/j.biocel.2015.02.003 PMID: 25681686.Plani-Lam, J. H. C., Chow, T. C., Siu, K. L., Chau, W. H., ...
Computational analysis of molecular basis of 1:1 interactions of NRG1beta wild-type and variants with ErbB3 and ErbB4. Proteins, 2005, 59(4): 742-756.LUO C,XU L F,ZHENG S X, et al.Computational analysis of molecularbasis of 1 : 1 interactions of NRG-1 beta wild-type and variants ...
Functional characterization of tyrosine phosphatase non-receptor 21, a novel modulator of ErbB4/NRG3Janice Lamlinxiaochu
Computational analysis of molecular basis of 1:1 interactions of NRG1beta wild-type and variants with ErbB3 and ErbB4. Proteins, 2005, 59(4): 742-756.Luo C,Xu L,Zheng S, et al.Computational analysis of molecular basis of 1:1interactions of NRG-1beta wild-type and variants with ErbB3...
(P<0.05),NRG-1,ErbB2和ErbB4蛋白表达减少(P<0.05);与Model组比较,人参皂苷Rb3干预的大鼠的心肌细胞炎症浸润及心肌纤维化程度减轻,心肌梗死面积,VE-cadherin表达水平降低(P<0.05),NRG-1,ErbB2和ErbB4蛋白表达增加(P<0.05).结论人参皂苷Rb3可通过调控Neuregulin-1/ErbB信号通路降低心肌梗死大鼠的心肌细胞的炎症...
Neuregulin 1 (NRG1); epidermal growth factor receptor 3 (EGFR3; HER3; ErbB3); HER4 (EGFR4; ErbB4)Cell culture and mouse studies suggest antagonizing NRG1, HER3 or HER4 could be useful for preventing chemotherapy resistance in NSCLC....