Research on the these mechanisms has been mainly focused on the cis-regulatory or transregulatory for the insecticide resistance-related genes, with less attention paid to non-coding RNAs (ncRNAs), such as microRNA (miRNA), long non-coding RNA (lncRNA), and circula...
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are not translated into proteins. Since their discovery, ncRNAs have emerged as important regulators of multiple biological functions across a range of cell types and
Functional Roles of Long Non-coding RNAs in Motor Neuron Development and Disease Long non-coding RNAs (lncRNAs) have gained increasing attention as they exhibit highly tissue- and cell-type specific expression patterns. LncRNAs are highly expressed in the central nervous system and their r... ...
Non-coding RNAs (ncRNAs) are ribonucleic acid (RNA) molecules that are not translated into protein products. Different classes of non-coding RNAs participate in different cellular processes; for example, gene expression regulation (miRNAs, piRNAs, lncRNAs), RNA maturation (snRNAs, snoRNAs) and prot...
Non-coding RNAs in development and disease: background, mechanisms, and therapeutic approaches Physiol. Rev., 96 (4) (2016), pp. 1297-1325 Google Scholar [6] C. Sun, L. Huang, Z. Li, K. Leng, Y. Xu, X. Jiang, Y. Cui Long non-coding RNA MIAT in development and disease: a ...
Long non-coding RNAs (lncRNAs) are RNA molecules over 200 nucleotides long, lacking protein-coding functions. Initially considered "junk"RNA, they are now recognized as crucial players in cellular processes like chromatin remodeling and gene expression regulation. Despite lacking coding potential, lncRNA...
Long non-coding RNAs (lncRNAs) comprise a diverse class of transcripts that can regulate molecular and cellular processes in brain development and disease. LncRNAs exhibit cell type- and tissue-specific expression, but little is known about the expressio
in the regulation ofchromatin structureand establishment of nuclear territories (Fig. 2;Bonasio & Shiekhattar, 2014;Dexheimer & Cochella, 2020). Non-coding RNAs are involved in all processes related to development and differentiation and are highly active as regulators ofneural developmentand mature ...
Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs) are widely expressed and have key roles in gene regulation. Recent studies have begun to unravel how the biogenesis of lncRNAs is distinct from that of mRNAs and is linked with their specific subcellular localizati...
Targeted protein degradation has become a notable drug development strategy, but its application has been limited by the dependence on protein-based chimeras with restricted genetic manipulation capabilities. The use of long non-coding RNAs (lncRNAs) has emerged as a viable alternative, offering interac...