Research progress on three different types of noncoding RNAs related to ionizing radiationMicroRNACircular RNALong noncoding RNAIonizing radiationNon-coding RNAs (ncRNAs) have attracted wide attention in the field of ionizing radiation (IR). They have been found to be involved in cell development, ...
This cap is uniquely found in small nuclear RNAs (snRNA) with a 5′ trimethylguanosine caps and in the long non-coding RNA (lncRNA) as 5′ monomethyl phosphate cap. In bacteria and some organisms, the mRNA is capped with NAD+, NADH, or 3′ dephospho-coenzyme A. In all organisms, mR...
Small non-coding RNAs (ncRNAs) are important regulators of gene expression in eukaryotes. Previously, only microRNAs (miRNAs) and piRNAs have been identified in the silkworm, Bombyx mori. Furthermore, only ncRNAs (50-500nt) of intermediate size have been systematically identified in the silkworm....
Small non-coding RNAs (ncRNAs) are important regulators of gene expression in eukaryotes. Previously, only microRNAs (miRNAs) and piRNAs have been identified in the silkworm, Bombyx mori. Furthermore, only ncRNAs (50-500nt) of intermediate size have been systematically identified in the silkworm....
et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 458, 223–227 (2009). Article CAS PubMed Central PubMed Google Scholar Marques, A.C. & Ponting, C.P. Catalogues of mammalian long noncoding RNAs: modest conservation and ...
MicroRNAs (miRNAs) are a highly abundant class of small (~22 nt), endogenous and evolutionarily con- served single-stranded non-coding RNAs that regulate the gene expression normally at post-transcriptional level by base pairing with their target mRNAs at 3′ untranslated regions (UTRs), ...
Multiplexed nucleotide-level perturbations or randomizations will be instrumental in calibrating GET for precise prediction of the functional impact of non-coding genetic variants. Determining the effects of non-coding variants in modulation of gene expression and disease susceptibility remains an important ...
Another set of spliceosomes termed ‘minor spliceosomes’ are also found in eukaryotic cells which have less abundant RNAs and are involved in the splicing of a rare class of pre-mRNA introns. RNA Splicing Process/ Mechanism The process of RNA splicing begins with the binding of the ribonucleop...
of cpMSCs, CSCs/CPCs, and CDCs, and pluripotent stem cells such as ESCs and iPSCs. Next-generation therapies for cardiac repair are directed toward cell enhancement (e.g., biomaterials, 3D cell constructs, cytokines, miRNAs) and cell-free concepts (e.g., growth factors, non-coding RNAs,...
In addition, miRNAs and long noncoding RNAs were not considered in this GCN analysis, both of which have been shown to modulate plant pathogen resistance50,51. Nevertheless, our estimates represent a genome-wide assessment of the number of protein-coding genes likely taking part in IM or HR ...