As important key players in gene regulatory networks, ncRNAs work with other biomolecules, including coding and non-coding RNAs, DNAs and proteins. In this review, we discuss the distinct types of ncRNAs, including housekeeping ncRNAs and regulatory ncRNAs, their versatile functions and interactions,...
Eukaryotic genomes are pervasively transcribed. Besides protein-coding RNAs, there are different types of non-coding RNAs that modulate complex molecular and cellular processes. RNA sequencing technologies and bioinformatics methods greatly promoted the
(2019a). Non-coding rnas and their integrated networks. Journal of integrative Bioinformatics, 16(3), 1–12. Article Google Scholar Zhang, X. T., Pan, S. X., Wang, A. H., Kong, Q. Y., Jiang, K. T., & Yu, Z. B. (2019b). Long non-coding RNA (lncRNA) X-Inactive ...
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are not translated into proteins. Since their discovery, ncRNAs have emerged as important regulators of multiple biological functions across a range of cell types and
Recently, many long non-coding RNAs (lncRNAs) have been identified and their biological function has been characterized; however, our understanding of their underlying molecular mechanisms related to disease is still limited. To overcome the limitation in experimentally identifying disease-lncRNA associatio...
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Non-Coding RNAs and their Integrated Networks. J. Integr. Bioinform. 2019, 16, 1–12. [Google Scholar] [CrossRef] [PubMed] Fernandes, J.C.R.; Acuña, S.M.; Aoki, J.I.; Floeter-Winter, L.M.; Muxel, S.M. Long Non-Coding RNAs in the Regulation of Gene Expression: Physiology...
Long noncoding RNAs (lncRNAs) have an important role in adipose tissue function and energy metabolism homeostasis, and abnormalities may lead to obesity. To investigate whether lncRNAs are involved in childhood obesity, we investigated the differential expression profile of lncRNAs in obese children comp...
A large number of evidence has demonstrated that non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs have functional roles in both the physiological and pathological processes by regulating the expression of their target genes. These molecules ...
Long noncoding RNAs (lncRNAs) are actively transcribed genes that do not “appear” to code for proteins. Emerging evidence suggests that lncRNAs serve as key regulators of atherosclerosis and related risk factors. A remarkable feature of lncRNAs is that they are expressed with potent specificity. ...