2020年2月17日,《白血病》(Leukemia)杂志发表了中山大学肿瘤防治中心林桐榆教授团队,一项建立NK/T细胞淋巴瘤(简称NK/T淋巴瘤)新分期系统的研究,这项研究来自中国和亚洲淋巴瘤协作组的多中心研究(A proposal for a new staging system for extranodal...
中国抗癌协会血液肿瘤专业委员会常委 近五年以通讯作者(含共同)在Blood、SignalTransduction and Targeted Therapy、ClinicalCancer Research、Leukemia等国际权威杂志发表SCI论文20余篇。主持国家自然科学基金共5项,包括国家自然科学基金重点项目...
Accordingly, a higher frequency of Tand NK/T-cell leukemia would be expected in East Asia. As compared to B-cell lymphomas, Tand NK/Tcell neoplasms more frequently occur at extranodal locations, and may occasionally present as leukemia, either with or without concomitant lymphoma....
2019年12月24日,由中山大学肿瘤防治中心牵头,联合来自全国九省/直辖市和港澳台地区、新加坡、韩国、美国等多家机构,组成国际研究团队继续在Lancet Oncology杂志上发表了题为“Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations”的文章,再次发现结外...
Natural killer/T-cell lymphoma (NKTL) is a sub-type of Epstein–Barr virus (EBV)-related non-Hodgkin lymphomas common in Asia and Latin America but rare elsewhere. Its pathogenesis is complex and incompletely understood. Lymphoma cells are transformed fr
https://aacrjournals.org/clincancerres/article/26/20/5368/82812/Targeted-Natural-Killer-Cell-based-Adoptive [2]Rubnitz JE,et al.NKAML: a pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia. J Clin Oncol. ...
NK/T细胞淋巴瘤(Natural killer/T-cell lymphoma, NKTCL)是一种高度侵袭性的淋巴瘤亚型,主要影响亚洲和南美洲人群[1]。管目前有许多新的治疗策略,但NKTCL患者的治疗结局仍然有待进一步提升,特别是对于在一线非蒽环类药物治疗后复发或进展的患者,中位总生存期仅6.4个月,中位无进展生存期仅4.1个月[2]。并且由于其...
Nk CellRibosome-LAMELLA ComplexA 36-year-old male was admitted to the hospital with anemia and leukopenia. A bone marrow specimen revealed the proliferation of leukemic cells with flower-like nuclei observed in adult T-cell leukemia. The leukemic cells were positive for HLA-DR, CD2, CD7, and...
对目前治疗方案不满意，或想寻求CAR-NK、NK细胞、CAR-T疗法等国内外更多抗癌新技术帮助的患者，可将近期病理及影像学检查报告、治疗经历等资料，提交至医学部，初步评估病情或申请国内外抗癌专家会诊。参考资料 [1]Zhang L,et al.CAR-NK cells for acute myeloid leukemia immunotherapy: past, present and future....
免疫系统是机体防卫病原体入侵最有效的武器,而NK细胞(Natural Killer Cell,自然杀伤细胞)作为其中的重要一员,虽然数量不多,但作用至关重要,是机体抗感染和识别并杀伤肿瘤细胞的重要免疫调节细胞,可谓我们抵抗疾病和保持健康的第一道防线。 01NK细胞发展历程 ...