NK/T细胞淋巴瘤（NK/T cell lymphoma）是起源于成熟NK/T细胞的淋巴系统恶性肿瘤。NK细胞和T细胞具有共同的祖细胞，两者在功能和某些抗原的表达上具有相似之处，NK/T细胞淋巴瘤因起源于这两种细胞而得名。NK/T细胞淋巴瘤在各年龄段均可发病，但主要见于成年人。Part 2病因是什么？本病病因不明。先天性或获得性免疫...
10. Sigrid De Wilde, Carlos Graux, Complete hematologic response in a patient with multiple pretreated angioimmunoblastic T‐cell lymphoma after belinostat therapy followed by allogeneic stem cell transplantation: A case rep...
NK/T细胞淋巴瘤临床治疗策略和放疗原则 结外鼻型NK/T细胞淋巴瘤(extranodal nasal--type Natural Killer/T-Cell lymphoma,NKTCL)具有独特的临床病理特征。东亚及拉丁美洲常见,而西方少见。中国结外鼻型NK/T细胞淋巴瘤发病率占全部淋巴瘤的11%~14%,占外周T细胞淋巴瘤...
Also referred to as polymorphic reticulosis, midline malignant reticulosis, Stewart's granuloma most of the lethal midline granulomas are NK/T-cell lymphomas. Untreated, this disease has a very high mortality reaching almost 100% due to septicemia, perforation into blood vessels or penetration into...
immunophenotype and genotype of the EBV-positive cells, B cell versus NK cell. ExtranodalNK/T-cell lymphoma arising in the skin, with no evidence of sinonasal a differential diagnosisof pleomorphic/transformed mycosis fungoides, peripheral T-cell lymphoma (PTCL), NOSG Yang...
NK/T淋巴瘤(自然杀伤/T细胞淋巴瘤,natural killer T-cell lymphoma )是具有特殊临床表现一类恶性非霍奇金淋巴瘤,主要发生于鼻咽和鼻腔。该疾病早期临床症状不明显,容易误诊和漏诊,常规淋巴瘤化疗方案治疗效果不敏感,晚期患者5年总生存率仍低于50%,复发难治是最终死亡的主要原因。因此,明确NK/T淋巴瘤致病相关因素,有...
NK/T细胞淋巴瘤(NK/T cell lymphoma)是一种罕见的、特殊类型的结外原发性非霍奇金淋巴瘤(NHL),其瘤细胞大部分来源于外周NK细胞,小部分来自NK样T细胞,有特定的免疫表型和基因型,其与人类疱疹病毒(HBV)感染高度相关。 按照原发部位分为鼻型和鼻外型,在我国以及亚洲其他国家、南美洲地区有较高的发病率,而在西欧...
Natural killer/T-cell lymphoma (NKTL) is a sub-type of Epstein–Barr virus (EBV)-related non-Hodgkin lymphomas common in Asia and Latin America but rare elsewhere. Its pathogenesis is complex and incompletely understood. Lymphoma cells are transformed fr
结外NK/T细胞淋巴瘤(extranodalNK/T-celllymphoma,ENKTCL)是一种少见的高侵袭性的非霍奇金淋巴瘤,其发病具有明显的地域和种族差异性,亚洲人群相对高发。ENKTCL恶性程度高、临床进展快、预后差,对其正确的诊断及治疗显得尤为重要。为了更好了解该疾病的生物学特性,探索治疗新措施的潜在靶点,本文就近几年ENKTCL的临床...
1、 nkt细胞淋巴细胞淋巴瘤瘤(nk/t cell lymphoma nktcl)潘燕秋潘燕秋症状:症状:该病呈血管中心性浸该病呈血管中心性浸润,血管损伤破坏,伴组润,血管损伤破坏,伴组织大片坏死,并与织大片坏死,并与ebeb病毒病毒密切相关,主要累及鼻腔、密切相关,主要累及鼻腔、鼻咽部、上颚、扁桃体、鼻咽部、上颚、扁桃体、下咽部...