Mahindhoratep S, Bouda HA, El Shafey N, Scherman D, Kichler A, Pichon Ch, Midoux P, Mignet N, Bureau MF. NF-kB related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotrans- fer. Biochim Biophys Acta 2014; 1840: 3257- 3263....
This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, ...
NFKB2 7.662133 17.90379 1.224447 8.12×10−28 7.86×10−27 NOD2 0.16621 0.925054 2.476529 3.32×10−31 5.32×10−30 S100A12 0.651347 1.641547 1.333557 8.53×10−9 1.39×10−8 TLR3 5.539797 15.88139 1.519433 3.19×10−24 1.61×10−23 PELI2 5.099336 2.198214 −1.21398 2.80×10−...
TheNFκB Profiling Plateincludes 88 promoter reporter constructs and 8 transfection control constructs (4 constructs from housekeeping genes with promoter activities of varying strengths (P1-P4), and 4 constructs with random 1 kb fragments (R1-R4)). To download a plate map with links to clone ...
How NF-kB is activated: the role of the IkB kinase (IKK) complex is in most cases the phosphorylation of the two N- terminal serines in the IkB molecule. As the E3IkB complex may also be involved in degradation of CD4 and b-catenin, the phosphorylation step is also the one that prov...
A 212-kb Region on Chromosome 6q25 Containing the TAB2 Gene Is Associated With Susceptibility to Type 1 Diabetes. which has homology to SUMO (small ubiquitin-related modifier) were found within the 212-kb region and were associated with type 1 diabetes susceptibility... Owerbach,David,Piña...
6D). Although decreased expression of other NF-KB-dependent genes in addition to c-FLIP and Mcl-1 was observed at 24 h after quinacrine exposure, sensitization to TRAIL or to l-OHP after IC25 concentrations of quinacrine pretreatment for 24 h was similar to the sensitization obtained with IC...
The potential relationship between p38 MAPK → COX2 and NF-kB → COX2 pathways were further explored. Simultaneous addition of SB203580 and Bay 11-7082 yielded an additive or synergistic effect on up-regulation of StAR expression and testosterone secretion in old Leydig cells. Perhaps bo...
The gene, which we named Nrf2 (NF-E2-related factor 2), is encoded within a 2.2-kb transcript and predicts a 66-kDa protein with a basic leucine zipper DNA binding domain highly homologous to that of NF-E2. Although Nrf2 is expressed ubiquitously, a role of this protein in mediating ...
The gene, which we named Nrf2 (NF-E2-related factor 2), is encoded within a 2.2-kb transcript and predicts a 66-kDa protein with a basic leucine zipper DNA binding domain highly homologous to that of NF-E2. Although Nrf2 is expressed ubiquitously, a role of this protein in mediating ...