Our data suggests that NF-κB may function as an antiapoptotic factor in thymocytes while functioning as a proapoptotic factor in mature peripheral T cells.doi:10.1038/sj.cdd.4400528Binhan LinCheryll Williams-SkippYunxia TaoMary S Schleicher
Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A. Oncogene,2003 22:4819-4830. 10.Wei-Hua Li, Jie Zhao, Hui-Y an Li, Hui Liu, Ai-Ling Li, Hong-Xia Wang, Jie Wang, Kun He, Bing Liang, Ming Y u, Bei-Fen Shen, and Xue...
These findings suggest that NIK governs metabolic rewiring, which is critical for balancing proinflammatory and anti-inflammatory myeloid immune cell function. Overall, our work highlights a previously unrecognized role for NIK as a molecular rheostat that fine-tunes immunometabolism in innate immunity, ...
function and activation of nf -kb in the immune system further annual reviews PA Baeuerle,T Henkel 被引量: 0发表: 0年 Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging the function of NF-kB system in the organization of defence ...
functionand symptoms in clinic. It haVe notledtosousefulin c1inicbecauseoftheadverse effects on lungs and other tissue. We compared methylDredni solone to NF—KB antisense oli gonucl eotides ontheeffectofbl eomycin induced Dulmonary fibrosis. The result indicates that ...
Uterine Progesterone Receptor Expression, Conceptus Development, and Ovarian Function in Pigs Treated with RU 486 During Early Pregnancy1 Establishment of pregnancy in the pig depends on down-regulation of progesterone receptor (PGR) in the uterine luminal and glandular epithelium during the ... DJ ...
H inz M ,Krappman n D ,Eichten A ,et a1.NF—KB function in growth contro l:regulation of cyclin D 1 expression and Go/G1-to-S—phase transition [J ].Mol Cell Biol,1999 , l 9 ( 4 ) :2690-2698. 孙艳香 ,廖玉华,朱 峰,等.俚l 肾上腺素受体 lA 亚型 ...
The Microbiology of NF-kBMany autoimmune diseases feature functional or genetic defects that can alter NF-kB function. In an animal model of type 1 diabetes and Sjogren's syndrome, a defective proteasome prevents NK-kB-induced gene transcription by precluding cleavage of IkBa from NF-kB in the...
[3] Parker JJ, Jones JC, Strober S, et al. Characterization of direct radiation-induced immune function and molecular. signaling changes in an antigen presenting cell line[J]. . Clin Immunol, 2013 , 148(1) : 4455. [4] de Azevedo MT, Saad ST.Gilli SC. IL4 and IFNalpha generation ...
Defects of the barrier function contribute to gastroesophageal reflux... H Chen,Y Fang,W Li,... - 《Tissue Barriers》 被引量: 12发表: 2013年 Nrf2在星形胶质瘤细胞外伤后炎症反应中作用的体外研究 目的现已证实脑外伤后Nrf2缺失可通过激活NF-κB加重炎症过程,但对脑外伤后星形胶质细胞内Nrf2与NF-κB...