Our data suggests that NF-κB may function as an antiapoptotic factor in thymocytes while functioning as a proapoptotic factor in mature peripheral T cells.doi:10.1038/sj.cdd.4400528Binhan LinCheryll Williams-SkippYunxia TaoMary S Schleicher
Function for NF-kB in neuronal survival: regulation by atypical protein kinase C. J Neurosci Res 1999;58:607-11... MW Wooten - 《Journal of Neuroscience Research》 被引量: 16发表: 2015年 Function for NF-kB in neuronal survival: Regulation by atypical protein kinase C Wooten MW. Function ...
function and activation of nf -kb in the immune system further annual reviews PA Baeuerle,T Henkel 被引量: 0发表: 0年 Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging the function of NF-kB system in the organization of defence ...
Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A. Oncogene,2003 22:4819-4830. 10.Wei-Hua Li, Jie Zhao, Hui-Y an Li, Hui Liu, Ai-Ling Li, Hong-Xia Wang, Jie Wang, Kun He, Bing Liang, Ming Y u, Bei-Fen Shen, and Xue...
The Microbiology of NF-kBMany autoimmune diseases feature functional or genetic defects that can alter NF-kB function. In an animal model of type 1 diabetes and Sjogren's syndrome, a defective proteasome prevents NK-kB-induced gene transcription by precluding cleavage of IkBa from NF-kB in the...
critical for balancing proinflammatory and anti-inflammatory myeloid immune cell function. Overall, our work highlights a previously unrecognized role for NIK as a molecular rheostat that fine-tunes immunometabolism in innate immunity, and suggests that metabolic dysfunction may be an important driver of ...
[3] Parker JJ, Jones JC, Strober S, et al. Characterization of direct radiation-induced immune function and molecular. signaling changes in an antigen presenting cell line[J]. . Clin Immunol, 2013 , 148(1) : 4455. [4] de Azevedo MT, Saad ST.Gilli SC. IL4 and IFNalpha generation ...
H inz M ,Krappman n D ,Eichten A ,et a1.NF—KB function in growth contro l:regulation of cyclin D 1 expression and Go/G1-to-S—phase transition [J ].Mol Cell Biol,1999 , l 9 ( 4 ) :2690-2698. 孙艳香 ,廖玉华,朱 峰,等.俚l 肾上腺素受体 lA 亚型 ...
function pulmonary symptoms l to c1inicbecauseoftheadverse noted sousefulin othertissue. We effects on and compared lungs soloneto NF—KB antisense methylDredni oli de on effectofbl induced eotis the eomycin gonucl es that fibrosis. Theresultindicat Dulmonary the ethedeathand failedtoreduc ...
effector caspases, including mammalian caspase-3 and fly drICE/DCP-1, can function as repressors of NF-κB-mediated innate immune signalings. 宿主生物使用不同的先天免疫机制来抵御病原体感染,而严格控制先天免疫对于适当的免疫诱导和平衡至关重要。在此,我们报告了细胞凋亡诱导或caspase-3过表达导致人类...