(1999). Function for NF-kB in neuronal survival: regulation by atypical protein kinase C. J. Neurosci. Res. 58, 607-611.Wooten MW. Function for NF-kB in neuronal survival: regulation by atypical protein kinase C. J Neurosci Res 1999;58:607-11....
critical for balancing proinflammatory and anti-inflammatory myeloid immune cell function. Overall, our work highlights a previously unrecognized role for NIK as a molecular rheostat that fine-tunes immunometabolism in innate immunity, and suggests that metabolic dysfunction may be an important driver of ...
Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A. Oncogene,2003 22:4819-4830. 10.Wei-Hua Li, Jie Zhao, Hui-Y an Li, Hui Liu, Ai-Ling Li, Hong-Xia Wang, Jie Wang, Kun He, Bing Liang, Ming Y u, Bei-Fen Shen, and Xue...
321. [3] Parker JJ, Jones JC, Strober S, et al. Characterization of direct radiation-induced immune function and molecular. signaling changes in an antigen presenting cell line[J]. . Clin Immunol, 2013 , 148(1) : 4455. [4] de Azevedo MT, Saad ST.Gilli SC. IL4 and IFNalpha genera...
effector caspases, including mammalian caspase-3 and fly drICE/DCP-1, can function as repressors of NF-κB-mediated innate immune signalings. 宿主生物使用不同的先天免疫机制来抵御病原体感染,而严格控制先天免疫对于适当的免疫诱导和平衡至关重要。在此,我们报告了细胞凋亡诱导或caspase-3过表达导致人类...
The Microbiology of NF-kBMany autoimmune diseases feature functional or genetic defects that can alter NF-kB function. In an animal model of type 1 diabetes and Sjogren's syndrome, a defective proteasome prevents NK-kB-induced gene transcription by precluding cleavage of IkBa from NF-kB in the...
ＮＦ—ＫＢ对ＴＮＦ—ａ基因转录的调控及其与两型ＴＮＦ一Ⅸ生物学功能的相互影响 全文摘要 ／ ｆ肿瘤坏死因子一ａ（ｔｕｍｏｒｎｅｃｒｏｓｉｓｆａｃｔｏｒ一Ⅸ，ＴＮＦ—ａ）是一种具有广泛生物学功能的细胞因子，其基因的表达受核因子一ｎＢ（ｎｕｃｌｅａｒｆａｃｔｏｒ－Ｋ）？ｒＴ－ＮＦ—ＫＢ）的调节。同...
(NLS) function. These inhibitor proteins, which include IkBa, IkBb and IkBg, contain 6–7 ankyrin repeats that mediate binding to the RHD. These repeats are also present in the C-terminal halves of the NF-kB2/p100 and NF-kB1/p105 precursors, which also function as IkBs and retain ...
TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech. 2000 Aug 1;50(3):184-95.[2]. Xi Rui, et al. RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma. Front Oncol. 2022 Jun 30:12:804439.[3]. Jang DI, et al...
functionand symptoms inclinic.IthaVe notledtosousefulinc1inicbecauseoftheadverse effectson lungs andothertissue.We compared methylDredni solonetoNF—KBantisense oli gonucl eotidesontheeffectofbl eomycin induced Dulmonaryfibrosis.Theresultindicatesthat methyl口rednis010nefailedtoreducethedeathandthe lossof...