Figure 1. ISRE-Luc NFκB-SEAP THP-1 细胞模型原理图 III. Introduction Host Cell: THP-1 Expressed gene: ISRE Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) Synonym(s): NF-kB reporter, NFkappaB reporter, luciferase ...
TLR4/NF-kB/SEAP Stable Reporter Cell Line imgenex 1Vial 18244 2-3周 在线询价 翌圣生物科技(上海)股份有限公司 类型: 生产厂家 联 系 人: 曹女士 电话: 400-6111-883 传真: 86-21-34615995 手机: 联系我时,请说明在化工仪器网上看到的,谢谢。
RAW-Blue™ cells are derived from RAW 264.7 macrophages. They stably express a secreted embryonic alkaline phosphatase (SEAP) gene inducible by NF-kB and AP-1 transcription factors. Upon TLR, NOD or Dectin-1 stimulation, RAW-Blue™ cells activate NF-
NF-kB/SEAP Stable Reporter Cell Line /NF-kB/SEAP稳转报告细胞株 参考价:面议 具体成交价以合同协议为准 产品型号 品牌 生产商厂商性质 上海市所在地 访问次数:1353更新时间:2023-03-15 09:14:46 产品分类品牌 翌圣生物科技(上海)股份有限 初级会员·13年 ...
These cell lines express an NF-κB-inducible SEAP (secreted embryonic alkaline phosphatase) and an IRF-inducible Lucia luciferase reporter gene. Both reporter proteins are readily measurable in the cell culture supernatant when usingQUANTI-Blue™, a SEAP detection reagent, andQUANTI-Luc™ 4 Lucia...
Figure 1. ISRE-Luc NFκB-SEAP THP-1 细胞模型原理图 III. Introduction Host Cell: THP-1 Expressed gene: ISRE Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) Synonym(s): NF-kB reporter, NFkappaB reporter, luciferase ...
现有的nf-κb活化报告细胞大多是以分泌型的碱性磷酸酶(seap)作为报告系统通过显色反应进行检测(www.invivogen.com),seap检测灵敏度有待进一步提高。其次几乎所有的报告细胞缺少内参报告系统,无法对细胞数量和细胞毒性引起的差异进行校正。 参考文献: 1.liouhc,baltimored.regulationofthenf-kappab/reltranscriptionfactor...
结果: JSH-23 以剂量依赖的方式抑制 LPS 诱导的 SEAP 表达,3 µM 时抑制 23±3%,10 µM 时 68±3%,30 µM 时 103±4%。JSH-23 抑制 NF-κB 转录活性。[2] 体内活性 方法: 为研究在糖尿病神经病变中的作用,将 JSH-23 (1-3 mg/kg) 口服给药给 streptozotocin 诱导的糖尿病大鼠,每天一次,...
S2979CU-T12-9CU-T12-9 is a specific agonist ofToll-like receptor (TLR) 1/2with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 signals throughNF-κBand invokes an elevation of the downstream effectorsTNF-α...
[0005]现有的NF-kB活化报告细胞大多是以分泌型的碱性磷酸酶(SEAP)作为报告系统通 过显色反应进行检测(www. invivoGen. com),SEAP检测灵敏度有待进一步提高。其次几乎所 有的报告细胞缺少内参报告系统,无法对细胞数量和细胞毒性引起的差异进行校正。 [0006] 参考文献: [0007] l.Liou HC,Baltimore D.Regulation ...