NF-κB–SEAP reporter HEK293 cells expressing human TLR2 and knockout for human TLR1 and TLR6 HEK‑Blue™ hTLR2 KO-TLR1/6 cells are a convenient tool to study the TLR2 signaling pathways as the control for HE
HEK-Blue-Lucia™ hTLR2 (NF/IL8) Cells (NF-κB-SEAP/KI-[IL-8]Lucia) NF-κB and IL-8 reporter HEK293 cells expressing human TLR2 Catalog code: hkd-htlr2ni https://www.invivogen.com/hek-blue-lucia-htlr2 For research use only Version 23E24-MM PRODUCT INFORMATION Content • ...
Zymosan stimulated NF-κB signaling in the line, but rhTSG-6 had no effect in the parent cell line that did not express CD44. Stable expression of CD44 in the cell line decreased the response to zymosan (Figure 5B), an observation consistent with the negative regulation of TLR2 signaling ...
HEK‑Blue™ hTLR2 cells were obtained by co-transfection of the hTLR2 and SEAP (secreted embryonic alkaline phosphatase) reporter genes. The SEAP reporter gene is placed under the control of the IFN-β minimal promoter fused to five NF-κB and AP-1-binding sites. Additionally, the ...