neutrophil extracellular trap formation通路解释 中性粒细胞外围陷阱形成(neutrophil extracellular trap formation,NETosis)是一种特殊的中性粒细胞死亡方式,用于对抗细菌和其他病原体的感染。 NETosis过程包括以下几个步骤: 1.活化:中性粒细胞受到感染或其他刺激后,会经历一系列内部信号转导事件的激活,包括细胞膜上的...
The impact of phillyrin on oxidative stress, neutrophil extracellular trap (NET) formation, and neutrophil accumulation was evaluated by measuring CD11b+Ly6G+cells, MPO, CitH3, extracellular DNA ratio, and oxidative stress markers. In vitro studies assessed the effects of phillyrin on oxidative ...
NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis. Infect. Immun. 82, 1766–1777 (2014). PubMed PubMed Central Google Scholar Sorensen, O. E. et al. Papillon-Lefevre syndrome patient reveals species-dependent requirements for neutrophil defenses. J. Clin. ...
(Fig.2band Extended Data Fig.4a). The ability of diphenyleneiodonium chloride (DPI) to inhibit NET formation in cells from MICL-deficient animals revealed the dependence of this response on NADPH oxidase (Extended Data Fig.4c). MICL transduces intracellular inhibitory signals through SHP1/2 (ref...
Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes Stephen Chu-Sung Hu, Hsin-Su Yu, Feng-Lin Yen, Chi-Ling Lin, Gwo-Shing Chen & Cheng-Che E. Lan Scientific Reports volume 6, Article number: 31119 (2016) ...
Extracellular-trap-formation-in-kuruma-shrimp-Marsupenaeus-japonicus-hemocytes-is-coupled-with-c-type-lysozyme_2016_Fish-Shellfish-Immunology 热度: the function(s) provided by the adenovirus-specified, dna-binding protein required for viral late gene expression is independent of the role of the ...
Neutrophil extracellular traps (NETs) — formation and :中性粒细胞外的陷阱(网)的形成和 热度: 中性粒细胞胞外网状陷阱 热度: 多肌炎中性粒细胞胞外陷阱特征 热度: 相关推荐 RESEARCHARTICLE NeutrophilExtracellularTrapFormationIs IndependentofDeNovoGeneExpression GabrielSollberger* ☯ ,BorkoAmulic* ☯...
Neutrophils play an immune defense role by releasing the proteases such as neutrophil elastase and myeloperoxidase to form neutrophil extracellular trap (NET) and participate in the inflammatory response of various liver diseases, but the excessive re
Since we had observed that neutrophils and other granulocytes release mitochondrial DNA (mtDNA) in the formation of extracellular DNA traps3, we hypothesized that mitochondrial dynamics might be important for mtDNA release. Five members of the GTPase dynamin family, namely mitofusin-1 (MFN1), mitofusi...
TcpC is a multifunctional virulence factor of uropathogenic E. coli (UPEC). Neutrophil extracellular trap formation (NETosis) is a crucial anti-infection mechanism of neutrophils. Here we show the influence of TcpC on NETosis and related mechanisms. We s