neutrophil extracellular trap formation通路解释 中性粒细胞外围陷阱形成(neutrophil extracellular trap formation,NETosis)是一种特殊的中性粒细胞死亡方式,用于对抗细菌和其他病原体的感染。 NETosis过程包括以下几个步骤: 1.活化:中性粒细胞受到感染或其他刺激后,会经历一系列内部信号转导事件的激活,包括细胞膜上的...
中性粒细胞杀菌主要通过两种方式:一种是通过直接吞噬病原体的方式,这也是认识最早,较为经典的方式;另一种是中性粒细胞坏死或者凋亡后会形成一种特殊的结构,称为NETs(neutrophil extracellular traps),它是中性粒细胞重要的杀菌利器,存在于脓液中,中性粒细胞虽然死了,但是它却能通过这种方式继续杀灭细菌. ...
Besides intracellular killing, neutrophils are able to exert an antibacterial activity in the extracellular space by the formation of so-called neutrophil extracellular traps (NETs)1,2. NETs consist of DNA and granule proteins and are able to bind and to kill extracellular pathogens. Thus, NETs re...
neutrophil extracellular trap formation is independent of de novo gene expression.中性粒细胞胞外陷阱形成独立于新创的基因表达.pdf 2016-12-28上传 neutrophil extracellular trap formation is independent of de novo gene expression.中性粒细胞胞外陷阱形成独立于新创的基因表达 ...
neutrophilextracellularnovoformationtrap粒细胞 RESEARCHARTICLE NeutrophilExtracellularTrapFormationIs IndependentofDeNovoGeneExpression GabrielSollberger* ☯ ,BorkoAmulic* ☯ ,ArturoZychlinsky DepartmentofCellularMicrobiology,MaxPlanckInstituteforInfectionBiology,Berlin,Germany ☯Theseauthorscontributedequallytothiswork...
"Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated vasculitis." Clin Exp Immunol 180(3): 408- 418.Tang S, Zhang Y, Yin SW, et al. Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated ...
Recent evidence suggests that enhanced neutrophil extracellular trap (NET) formation activates plasmacytoid dendritic cells and serves as a source of autoa... JS Knight,W Zhao,W Luo,... - 《Journal of Clinical Investigation》 被引量: 211发表: 2013年 Efficient Neutrophil Extracellular Trap Induction...
TcpC is a multifunctional virulence factor of uropathogenic E. coli (UPEC). Neutrophil extracellular trap formation (NETosis) is a crucial anti-infection mechanism of neutrophils. Here we show the influence of TcpC on NETosis and related mechanisms. We s
中性粒细胞的一个关键特征是它们能够将一种被称为中性粒细胞胞外陷阱(neutrophil extracellular trap,NET)的结构挤压到周围环境中。NET是一种由被有毒性的酶覆盖的DNA组成的网状结构,正常情况下能够捕获并杀死入侵的微生物。然而,越来越多的证据表明,NET介导了癌细胞侵袭特性的发展和增强,但它们是如何促进癌细胞转移的...
Superoxide Induces Neutrophil Extracellular Trap Formation in a TLR-4 and NOX-Dependent Mechanism Ahmed B Al-Khafaji,1 Samer Tohme,1 Hamza Obaid Yazdani,1 David Miller,2 Hai Huang,1,3 and Allan Tsung1 1Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh; Pennsylvania, ...