neutrophil extracellular trap formation通路解释 中性粒细胞外围陷阱形成(neutrophil extracellular trap formation,NETosis)是一种特殊的中性粒细胞死亡方式,用于对抗细菌和其他病原体的感染。 NETosis过程包括以下几个步骤: 1.活化:中性粒细胞受到感染或其他刺激后,会经历一系列内部信号转导事件的激活,包括细胞膜上的...
neutrophilextracellulartrapformationisindependentofdenovogene 系统标签: neutrophilextracellularnovoformationtrap粒细胞 RESEARCHARTICLE NeutrophilExtracellularTrapFormationIs IndependentofDeNovoGeneExpression GabrielSollberger* ☯ ,BorkoAmulic* ☯ ,ArturoZychlinsky DepartmentofCellularMicrobiology,MaxPlanckInstituteforInfec...
neutrophilextracellulartrapformationisindependentofdenovogene 系统标签: neutrophilextracellularnovoformationtrap粒细胞 RESEARCHARTICLENeutrophilExtracellularTrapFormationIsIndependentofDeNovoGeneExpressionGabrielSollberger*☯,BorkoAmulic*☯,ArturoZychlinskyDepartmentofCellularMicrobiology,MaxPlanckInstituteforInfectionBiology,...
Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated vasculitis. Clin Exp Immunol (2015) 180(3):408-18. doi:10.1111/cei.12589Neutrophil extracellular trap formation is associated with autophagy‐related signalling in ANCA‐associated vasculitis[J] . S...
Besides intracellular killing, neutrophils are able to exert an antibacterial activity in the extracellular space by the formation of so-called neutrophil extracellular traps (NETs)1,2. NETs consist of DNA and granule proteins and are able to bind and to kill extracellular pathogens. Thus, NETs re...
TcpC is a multifunctional virulence factor of uropathogenic E. coli (UPEC). Neutrophil extracellular trap formation (NETosis) is a crucial anti-infection mechanism of neutrophils. Here we show the influence of TcpC on NETosis and related mechanisms. We s
Stimulation of neutrophils with MRP-14 induced neutrophil extracellular trap (NET) formation, and NETs were reduced in venous thrombi harvested from Mrp-14... Y Wang,H Gao,CW Kessinger,... - 《Jci Insight》 被引量: 0发表: 2017年 加载更多来源...
Neutrophil extracellular trap (NET) formation contributes to gout, autoimmune vasculitis, thrombosis, and atherosclerosis. The outside-in signaling pathway triggering NET formation is unknown. Here, we show that the receptor-interacting protein kinase (RIPK)-1-stabilizers necrostatin-1 or necrostatin-1s...
Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps. J. Cell Biol. 191, 677–691 (2010). CAS PubMed PubMed Central Google Scholar Metzler, K. D. et al. Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate ...
Neutrophil extracellular traps (NETs) emerge from the cell as a DNA scaffold associated with cytoplasmic and granular proteins, able to immobilize and kill pathogens. This association occurs following nuclear and granular membrane disintegration, allowing contact with the decondensed chromatin. Thus, it ...