neutrophil extracellular trap formation通路解释 中性粒细胞外围陷阱形成(neutrophil extracellular trap formation,NETosis)是一种特殊的中性粒细胞死亡方式,用于对抗细菌和其他病原体的感染。 NETosis过程包括以下几个步骤: 1.活化:中性粒细胞受到感染或其他刺激后,会经历一系列内部信号转导事件的激活,包括细胞膜上的...
Intriguingly, we found that plasma induced profound extracellular trap formation. This was inhibited by the presence of catalase during plasma treatment but was not replicated by adding an equivalent concentration of hydrogen peroxide. Plasma-induced neutrophil extracellular trap formation was not dependent...
Neutrophil extracellular traps (NETs) — formation and :中性粒细胞外的陷阱(网)的形成和 热度: 中性粒细胞胞外网状陷阱 热度: 多肌炎中性粒细胞胞外陷阱特征 热度: 相关推荐 RESEARCHARTICLE NeutrophilExtracellularTrapFormationIs IndependentofDeNovoGeneExpression GabrielSollberger* ☯ ,BorkoAmulic* ☯...
(Fig.2band Extended Data Fig.4a). The ability of diphenyleneiodonium chloride (DPI) to inhibit NET formation in cells from MICL-deficient animals revealed the dependence of this response on NADPH oxidase (Extended Data Fig.4c). MICL transduces intracellular inhibitory signals through SHP1/2 (ref...
(ATP) production through glycolysis due to lowered NAD+availability. Additionally, we show that OPA1-dependent ATP production in these cells is required for microtubule network assembly and for the formation of neutrophil extracellular traps. Finally, we show thatOpa1N∆mice exhibit a reduced ...
citrullinated histone h3, a biomarker of neutrophil extracellular trap formation, predicts the risk of venous thromboembolism in cancer patients.[2 热度: neutrophil extracellular trap formation is associated with il-1β and autophagy-related signaling in gout 热度: The p33 auxiliary replicase ...
COPD is a progressive disease of the airways that is characterized by neutrophilic inflammation, a condition known to promote the excessive formation of neutrophil extracellular traps (NETs). The presence of large amounts of NETs has recently been demonstrated for a variety of inflammatory lung diseas...
Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps. J. Cell Biol. 191, 677–691 (2010). CAS PubMed PubMed Central Google Scholar Metzler, K. D. et al. Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate ...
Role of PTEN in neutrophil extracellular trap formation NETosis has been associated with a particular mode of cell death although it is still controversial as to what extent autophagy is involved in NETosis. Cla... S Teimourian,E Moghanloo - 《Molecular Immunology》 被引量: 17发表: 2015年 ...
Conversely to pDCs, PMNs can release DNA via so-called neutrophil extracellular trap (NET) formation, an activation-induced process leading to the extrusion of nuclear DNA7. In addition, cellular proteins are important components of NETs, and this includes LL378for which PMNs are also the main ...