All ChromoTek Nanobody-based reagents are now available on ptglab.com. Nano-Traps Nano-Traps是快速、可靠、高效的一步免疫沉淀和免疫共沉淀的理想选择。Nano-Traps由与琼脂糖珠或磁珠偶联的纳米体组成. Explore the range Nano-Secondaries Nano Secondaries® 是一种可以获得更高分辨率,更清晰图像的新型二抗...
All ChromoTek Nanobody-based reagents are now available on ptglab.com.Products Applications Nano-Traps Nano-Traps are ideal for fast, reliable and efficient one-step immunoprecipitation and co-immunoprecipitation. Nano-Traps comprise of Nanobodies conjugated to beads. Explore the range Nano-Secondary...
Nanobody-based ReagentsNanobodies are the smallest known antibodies (~12-15 kDa vs ~150 kDa of conventional IgG antibodies). They are the antigen binding domains or variable heavy domain of heavy chain antibodies (VHHs) from alpacas, llamas, or camels. ...
Nanobody-based assays can also exhibit superior performance for immunodetection. Here, we describe protocols for three nanobody-based immunoassays for the detection of small chemical contaminants in environmental or agricultural samples: enzyme-linked immunosorbent assay (ELISA), fluorescence enzyme ...
Chimeric antigen receptor-based T-cell immunotherapy is a promising strategy for treatment of hematological malignant tumors; however, its efficacy towards solid cancer remains challenging. We therefore focused on developing nanobody-based CAR-T cells th
B7-H3 nanobody-based CAR-T cells lyse human PDAC and NB tumor cells in vitro To generate B7-H3 CAR-T cells using the above nanobodies, we inserted individual VHH fragment into our CAR vector that is being used in the clinic (NCT05003895)21(Fig.4a). The human truncated epidermal growth...
NanobodyMycotoxinFluorescence resonance energy transferImmunoassayA noncompetitive and homogeneous fluorescence resonance energy transfer (FRET) immunoassay was developed using a nanobody (Nb) for highly sensitive and simultaneous detection of ochratoxin A (OTA) and ochratoxin B (OTB). The promoted ...
Here is an overview of our Nanobody-based tools for cancer research: P53-C-term-Trap & P53-N-term-Trap The tumor suppressor protein p53 plays a major role in cell cycle control, apoptosis, and senescence.ChromoTek offers two different p53-Traps for immunoprecipitation of the p53 proteome ...
Our method relies on nanobody-based sensors, which enable proximity detection between subunits in time-resolved Förster resonance energy transfer (FRET) measurements. Additionally, given conformation-specific nanobodies, the activation of these complexes can be recorded in native brain tissue. Applied ...
Stimulation of cPBMCs in the presence of agonistic anti-CD3 Ab and cHcAb6 significantly increased the expression of IFN-γ as compared to the isotype control. This study identifies a novel nanobody-based CTLA4 inhibitor for the treatment of canine cancer patients....