1. Nanobodies as therapeutics:big opportunities for small antibodies(2016); 2. Nanobody-based cancer therapy of solid tumors(2015); 3. Http://www.ablynx.com 4. Http://www.alphamab.com/
1. Nanobodies as therapeutics:big opportunities for small antibodies(2016); 2. Nanobody-based cancer therapy of solid tumors(2015); 3. Http://www.ablynx.com 4. Http://www.alphamab.com/ 相关会议推荐: 会议时间:2016年11月18-19日 地址:苏州...
Targeted therapyMonoclonal antibodies and vaccines have widely been studied for the immunotherapy of cancer, while their large size appears to limit their functionality in solid tumors, in large part due to unique properties of tumor microenvironment such as high pressure of tumor interstitial fluid. ...
Kijanka M, Dorresteijn B, Oliveira S, van Bergen en Henegouwen PM. Nanobody-based cancer therapy of solid tumors. Nanomedicine. 2015;10:161–74. ArticleCASPubMedGoogle Scholar Scully M, Cataland SR, Peyvandi F, Coppo P, Knöbl P, Kremer Hovinga JA, Metjian A, de la Rubia J, Pave...
Nanobody-based cancer therapy of solid tumors 2015, Nanomedicine View all citing articles on ScopusNote: S. Oliveira is supported by the STW-NWO Veni grant number (11878). R. Heukers is supported by the Focus & Massa project of the Utrecht University and by a grant from arGEN-X, Gent,...
ImmunoPET imaging of Trop2 expression in solid tumors with nanobody tracers. Eur J Nucl Med Mol Imaging. 2024;51:380–94. https://doi.org/10.1007/s00259-023-06454-3. Article PubMed CAS Google Scholar Download references Funding This work was supported in part by the National Key ...
M. Nanobody-based cancer therapy of solid tumors. Nanomedicine (Lond) 10, 161–174, doi: 10.2217/nnm.14.178 (2015). 11. Vaneycken, I. et al. In vitro analysis and in vivo tumor targeting of a humanized, grafted nanobody in mice using pinhole SPECT/ micro-CT. J Nucl Med 51, 1099...
Here, we developed nanobody (Nb)-based ICIs to elicit CTLA4 blockade and treat canine cancer patients. Nanobodies (Nbs), representing the variable fragments (VHH) of camelid heavy-chain-only antibodies (HcAbs), bind to antigens in the absence of a light chain14. Nbs are small in size (...
• Metastatic non-small cell lung cancer • Non-small cell lung cancerPhase 2 BI-836880Bispecific VHHANGPT2, ANGPTL2, VEGF, VEGFA, VEGFR• Solid tumors • Malignant tumors of the anus or anal canal • Malignant tumor of the gastrointestinal tract ...
Rational design of chimeric antigen receptor T (CAR-T) cells based on the recognition of antigenic epitopes capable of evoking the most potent CAR activation is an important objective in optimizing immune therapy. In solid tumors, the B7-H3 transmembrane protein is an emerging target that harbour...