The RNAN6-methyladenosine (m6A) modification has become an essential hotspot in epigenetic modulation. Serine鈥揳rginine protein kinase 1 (SRPK1) is associated with the pathogenesis of various cancers. However, the m6A modification of SRPK1 and its association with the mechanism of in lung ...
Chicago, IL 60637, USA; 4Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNAs (mRNAs), and plays important roles in cell differentiation and tissue developm...
et al. RNA N6-methyladenosine-modified-binding protein YTHDF1 promotes prostate cancer progression by regulating androgen function-related gene TRIM68. Eur J Med Res 28, 552 (2023). https://doi.org/10.1186/s40001-023-01533-5 Download citation Received31 July 2023 Accepted16 November 2023 ...
et al. N6-Methyladenosine-modified lncRNA LINREP promotes Glioblastoma progression by recruiting the PTBP1/HuR complex. Cell Death Differ 30, 54–68 (2023). https://doi.org/10.1038/s41418-022-01045-5 Download citation Received21 August 2021 Revised05 July 2022 Accepted11 July 2022 Published23...
N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer Zhenchuan Liu, Tingting Wang, Yunlang She, Kaiqing Wu, Shaorui Gu, Lei Li, Chenglai Dong, Chang Chen...
Methylated RNA immunoprecipitation (MeRIP) was performed to detect the N6-methyladenosine (m6A) modification. RNA immunoprecipitation (RIP) was used to detect the interaction of AGAP2-AS1 with YTH domain family 2(YTHDF2). The relationships among AGAP2-AS1, miR-424-5p and AKT3 were examined by...
YTHDC2 regulates spermatogenesis through promoting the translation of N6-methyladenosine-modified RNAdoi:10.1096/fasebj.31.1_supplement.595.10John Wiley & Sons, LtdThe FASEB Journal
[14]. Furthermore, growing evidence suggests that m6A modification is also present in ncRNAs including circNRAs [15]. For example, N6-methyladenosine-modified circPLPP4 sustains cisplatin resistance in ovarian cancer cells via PIK3R1 upregulation [16]. ALKBH5-mediated m6A modification of circCCDC...
N6-methyladenosine-modified circ_0000337 sustains bortezomib resistance in multiple myeloma by regulating DNA repairdoi:10.3389/fcell.2024.1383232Siyi JiangLili GaoJian LiFangrong ZhangYanan ZhangJing LiuFrontiers in Cell & Developmental Biology
n6-methyladenosine-modified circular RNA family with sequence similarity 126, member A affects cholesterol synthesis and malignant progression of prostate cancer cells by targeting microRNA-505-3p to mediate calnexindoi:10.7150/jca.89135METHYLADENINE-DNA glycosylase...