N6-甲基腺苷-生物素缀合物上海齐源生物科技有限公司 产品详细介绍:齐源生物现货产品:N6-甲基腺苷-生物素缀合物规格:1mg储存条件:-15℃避光防潮保质期:24个月现货产品物理化学光谱特性分子量:753.87外观:固体溶剂:DMSO现货产品介绍N-6甲基腺苷(m6A)是目前已知的100余种RNA甲基化修饰中最普遍存在的一种,存在于某些...
FTOm6Amitochondriaoxidative stressPGC‐1αThe abundant and reversible N6‐methyladenosine (m6A) RNA modification and its modulators have important roles in regulating various gene expression and biological processes. Here, we demonstrate that fat mass and obesity associated (FTO), as an m6A demethylase,...
原名:N6-methyladenosine reader YTHDF1 promotes ARHGEF2 translation and RhoA signaling in colorectal cancer 译名:N6-甲基腺苷读取器YTHDF1在结直肠癌中促进ARHGEF2翻译和RhoA信号转导 期刊:Gastroenterology IF:22.682 发表时间:20...
et al. RNA N6-methyladenosine demethylase FTO targets MOXD1 promoting the malignant phenotype of gastric cancer. BMC Gastroenterol 24, 29 (2024). https://doi.org/10.1186/s12876-023-03065-y Download citation Received22 May 2023 Accepted28 November 2023 Published10 January 2024 DOIhttps://doi....
N6-Methyladenosine (m6A) is the most prevalent internal modification of messenger RNA (mRNA) in eukaryotes. The underlying molecular mechanisms of m6A modification in chronic glomerulonephritis (CGN) remain unexplored. Here, we performed methylated RNA immunoprecipitation sequencing (MeRIP-seq) and RNA se...
N6-methyladenosine (m6A) has emerged as an abundant modification throughout the transcriptome with widespread functions in protein-coding and noncoding RNAs. It affects the fates of modified RNAs, including their stability, splicing, and/or translation,
英文名称:N6-Methyladenosine CAS No.:1867-73-8 分子式:C11H15N5O4 分子量:281.2679 如需查看该化合物的详细结构式,mol文件,smile,InChi 请点击:N6-甲基腺嘌呤结构式 下载该化合物MOL文件:N6-甲基腺嘌呤MOL PubChem CID:102175 快速询单 N6-甲基腺嘌呤的其他展现形式 ...
Here, we show that the 18S rRNA N6-methyladenosine (m6A) methyltransferase complex METTL5–TRMT112 is upregulated in various cancer types and correlated with poor prognosis. In addition, we demonstrate the critical functions of METTL5 in promoting hepatocellular carcinoma (HCC) tumorigenesis in ...
Internal N6-methyladenosine (m6A) modification is one of the most common and abundant modifications of RNA. However, the biological roles of viral RNA m6A remain elusive. Here, using human metapneumovirus (HMPV) as a model, we demonstrate that m6A serves as a molecular marker for innate immun...
N6-methyladenosine modification controls circular RNA immunity. Mol Cell. 2019;76(1):96–109.e9. Article CAS PubMed Google Scholar Winkler R, Gillis E, Lasman L, Safra M, Geula S, Soyris C, et al. m(6)A modification controls the innate immune response to infection by targeting type ...