N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol 2011;7:885-7.Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y, Yi C, Lindahl T, Pan T, Yang YG, et al. N6-methyladenosine in nuclear RNA is a major sub- strate of the obesity-...
m6A(N6-腺苷酸甲基化,N6-methyladenosine)作为丰度最高的RNA修饰形式,在HCV病毒感染中起重要作用,通过修饰病毒RNA以及细胞转录产物影响病毒感染。 2023年3月24日,华中科技大学同济医学院石春薇课题组在Virology上发表了题为“Research progress on the role of RNA N6-methyladenosine methylation in HCV infection”的最...
The N6‐methyladenosine (m6A) modification is the most common modification of messenger RNAs in eukaryotes and has crucial roles in multiple cancers, including in urological malignancies such as renal cell carcinoma, bladder cancer and prostate cancer. The m6A RNA modification is controlled by three ...
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO (vol 7, pg 885, 2011). Nat Chem Biol, 2012, 8(12): 1008-1008.Jia G,Fu Y,Zhao X,Dai Q Zheng G Yang Y. N6-methyladenosine in nuclear ... G Jia,Y Fu,X Zhao,... - 《Nature Chemical Biology》...
Jia, G., Fu, Y., Zhao, X., Dai, Q., Zheng, G., Yang, Y., Yi, C., Lindahl, T., Pan, T., Yang, Y.G., and He, C. (2011). N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat. Chem. Biol.7,885-887. ...
Identification of methylated nucleosides in messenger RNA from novikoff hepatoma cells [J]. PNAS, 1974, 71(10): 3971-3975. [2] JIA G F, FU Y, ZHAO X, et al. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO[J]. Nat Chem Biol, 2011, 7(12): ...
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011;7:885–7. Article CAS Google Scholar Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, Jia G, Yu M, Lu Z, Deng X, et al. A METTL3-METTL14 complex mediates mammalian ...
N6-Methyladenosine是mRNA中一种丰富的碱基修饰的腺苷类似物,发现于一些病毒和大多真核生物,包括哺乳动物,昆虫,植物和酵母。它也被发现于tRNA,rRNA,和小核RNA(snRNA)以及一些长链非编码RNA,如Xist。 N6-Methyladenosine是转运核糖核酸(tRNA)降解的一种内源性尿核苷产物。 在许多组织中,N6-Methyladenosine是广泛存在的RN...
N6-methyladenosine (m6A)是碱基修饰的腺苷类似物,在天然RNAs中作为稀有核苷。N6-methyladenosine(m6A)是mRNA的第五种碱基 溶解性:DMSO : 56 mg/mL (199.09 mM) Ethanol : 2 mg/mL (7.11 mM) Water : 14 mg/mL (49.77 mM) 体外研究: N6-Methyladenosine is an abundant modification in mRNA and is found...
RNA modifications, including N6-methyladenosine (m6A), have been reported to regulate fundamental RNA processes and properties, and directly linked to various human diseases. Methods enabling temporal and transcript/locus-specific editing of specific RNA