N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011;7(12):885-7.Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y, et al. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol 2011;...
& Pang, D. Targeting RNA N6-methyladenosine modification: a precise weapon in overcoming tumor immune escape. Mol. Cancer 21, 176 (2022). Article CAS PubMed PubMed Central Google Scholar Jia, G. et al. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO....
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat. Chem. Biol. 7, 885–887 (2011). Article CAS PubMed PubMed Central Google Scholar Zheng, G. et al. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol. ...
在细胞核中 FTO 作用底物为多聚腺苷酸(polyA)RNA 中的 m6A、核小 RNA(small nuclear RNA,snRNA)中的N6,2'-O-二甲基腺苷(N6,2'-O-dimethyladenosine,m6Am)、tRNA 中的 m1A;而在细胞质中则是 polyA RNA 中的 m6A 和m6Am...
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO (vol 7, pg 885, 2011). Nat Chem Biol, 2012, 8(12): 1008-1008.Jia G,Fu Y,Zhao X,Dai Q Zheng G Yang Y. N6-methyladenosine in nuclear ... G Jia,Y Fu,X Zhao,... - 《Nature Chemical Biology》...
RNA化学修饰是近年来相关领域的研究热点,包括在腺嘌呤、鸟嘌呤、胞嘧啶等碱基发生的甲基化、乙酰化等修饰,其中甲基化是最主要的修饰形式。m6A(N6-腺苷酸甲基化,N6-methyladenosine)作为丰度最高的RNA修饰形式,在HCV病毒感染中起重要作用,通过修饰病毒RNA以及细胞转录产物影响病毒感染。
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011;7(12):885–7. Article CAS PubMed PubMed Central Google Scholar Mauer J, Luo X, Blanjoie A, Jiao X, Grozhik AV, Patil DP, et al. Reversible methylation of m(6)A(m) in ...
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011;7:885–7. Article CAS Google Scholar Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, Jia G, Yu M, Lu Z, Deng X, et al. A METTL3-METTL14 complex mediates mammalian ...
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat. Chem. Biol. 7, 885–887 (2011). Article CAS PubMed PubMed Central Google Scholar Zheng, G. et al. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol. ...
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat. Chem. Biol. 7, 885–887 (2011). Article CAS Google Scholar Tang, C. et al. ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells. Proc. ...