黑素瘤miR-675-3p预后生物标志物信号通路生物信息学目的:皮肤黑素瘤是皮肤肿瘤中恶性程度最高的一种,居皮肤恶性肿瘤死亡率第一位,其发病率的增长速度比目前任何其他可预防的皮肤肿瘤都要快.早期诊断后,手术切除一般预后良好,一旦发生转移,仍然缺乏有效的治疗手段,患者生存率急剧下降.尽管目前靶向治疗的应用和免疫治疗...
英文名称:mmu-miR-675-3p agomir品牌厂商性质产地货期价格 MedChemExpress (MCE) 生产商 美国 现货 ￥1800 性能特点 mmu-miR-675-3p agomir 是一种经过特殊化学修饰的miRNA模拟物,miRNA成熟链全链进行甲氧基修饰,在5'端和3'端分别有2个和4个硫代骨架修饰,并在3'端连接有高亲和性 ...
英文名称:mmu-miR-675-3p mimic品牌厂商性质产地货期价格 MedChemExpress (MCE) 生产商 美国 现货 ￥960 性能特点 mmu-miR-675-3p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 在线咨询 询底价 ...
货号:mml-miR-675-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:mml-miR-675-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
Furthermore, SOCS5, an endogenous inhibitor of the STAT3 pathway, was a direct target of miR-675-3p, which was positively regulated by H19 in PC cells.Conclusions:The H19/miR-675-3p signaling axis plays a critical role in maintaining the EMT process and stemness of PC cells by directly...
王不留行黄酮苷通过miR-570-3p/BNIP3减轻线粒体损伤并缓解2型糖尿病内皮功能障碍 目的:探究王不留行黄酮苷(VAC)对2型糖尿病(T2DM)内皮功能障碍的治疗作用及机制研究.方法:(1)通过腹腔注射链脲佐菌素和喂饲高脂饲料(21.8 kJ/kg,60%能量为脂肪)构建T2D... 赵晨阳,朱雪雪,陈欣雨,... - 《中国病理生理...
Through upstream and downstream analyses of miR-675-3p-related regulatory activity, we confirmed that this miRNA participates in key melanoma-related processes and offers value as a prognostic biomarker in melanoma patients.doi:10.1007/s13577-020-00473-0Cai-Chou Zhao...
Of those, upregulated miR-675-3p expression was successfully validated in the same cohort by qPCR experiments. Conversely, miR-675-3p expression levels were significantly decreased in the non-TRS cohort (50 controls vs. 50 patients without TRS without clozapine treatment)....
As expected, these lncRNA H19-expressing cells exhibited miR-675-3p in the E18.5 placenta. Intriguingly, miR-675-3p was also present in H19-negative spongiotrophoblast cells and syncytiotrophoblasts, implying the possible transfer of miR-675-3p from H19-exprssing cells to adjacent H19-non...
doi:10.1080/15622975.2024.2349065Kyle HewittXu-Feng HuangWorld Journal of Biological Psychiatry