KREMEN2PI3K/AKTLINC02247miR-6747-3p目的:卵巢癌是当下发病率较高的癌症之一,对妇女的健康构成严重威胁.当疾病扩散到其他盆腔器官时,由于肿瘤细胞减灭术和肿瘤治疗的疗效有限,治愈率大大降低.几十年来卵巢癌患者的生存率都没有明显提高,诊断后5年的生存率仍然很低,仅为44%.相比之下,乳腺癌的5年生存率为89%....
Functionally, miR-6747-3p overexpression resulted in the hindrance of cell proliferation, promotion of cell apoptosis, facilitation of cellular erythroid differentiation and γ-globin expression in HUDEP-2 and K562 cells. Mechanistically, miR-6747-3p could specifically bind to the 546...