bmo-miR-375-5p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:bmo-miR-375-5p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:bmo-miR-375-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
hsa-miR-375和hsa-miR-183-5p表达显著降低(p<0.05);hsa-miR-375和hsa-miR-183-5p过表达质粒转染HEC-1B后,细胞增殖能力明显降低,细胞凋亡百分比提高,TP53,Bax的mRNA表达水平显著提高,Bcl-2的mRNA表达水平显著降低(p<0.05).研究结果表明,hsa-miR-375和hsa-miR-183-5p可通过调控凋亡相关基因的表达促进HEC-1B...
The ability of miR-199a-5p and miR-375 to target PHLPP1 (PH domain and leucine-rich repeat protein phosphatase 1), a tumor suppressor that negatively regulates the AKT pathway, accounts, at least in part, for their drug-resistance activity. Indeed, restoration of PHLPP1 increases sensitivity...
Overexpression of miR-497-5p, miR-195-5p and miR-455-3p inhibited A375 cell proliferation, migration and invasion, arrested the cell cycle, induced cell apoptosis and decreased hTERT expression at both mRNA and protein levels. Sup- pression of miR-497-5p, miR-195-5p and miR-455-3p ...
恶性黑素瘤中调控hTERT基因相关miRNAs的筛选与功能研究 显示,miR-497-5p,miR-195-5p和miR-455-3p通过与hTERT基因3'UTR区直接结合参与调控恶性黑素瘤的发生和发展.结论:在人恶性黑素瘤中,miR-497-5p,miR-195-5p... 柴莉 - 新疆医科大学 被引量: 0发表: 0年...
Patients with advanced diseases had higher miR-210-3p expression (Figure 2, Table S1), while a slight decrease in miR-210-3p expression was associated with a better survival (Figure 3, Table S1). Figure 1. TCGA miR-375-3p, miR-210-3p, and let-7e-5p expression according to PAM50 ...
The calculated Area under curve (AUC) levels showed that miR-196a-5p (AUC: 0.64; 95% CI: 0.521–0.759;=0.032) for obstructive CAD and STEMI groups, miR-373-3p (AUC: 708; 95% CI: 0.605–0.812;) for STEMI group and miR-375 (AUC: 0.722; 95% CI: 0.635–0.808;<) for obstructive...
The ability of miR-199a-5p and miR-375 to target PHLPP1 (PH domain and leucine-rich repeat protein phosphatase 1), a tumor suppressor that negatively regulates the AKT pathway, accounts, at least in part, for their drug-resistance activity. Indeed, restoration of PHLPP1 increases sensitivity...
Expression of serum miR-1-3p, miR-96-5p, miR-148a-3p, and miR-375-3p was decreased in PCa patients when compared to BPH samples. Diagnostic accuracy of combinations of PSA with geometric means of [miR-1-3p, miR-148a-3p], [miR-148a-3p, miR-375-3p], and [miR-375-3p, miR-96...
Enrichment analysis of GC-associated genes in miR-148a-3p, miR-204-5p, miR-223-3p and miR-375 target genes by using hypergeometrical distribution.Simonas JuzenasVioleta SaltenienėJuozas KupcinskasAlexander LinkGediminas Kiude...