miR-454-3p目的:胶质瘤是成人最常见的原发性恶性脑瘤.虽然在胶质瘤的诊断和治疗方面已取得了重大的进展,但是胶质瘤患者的预后仍然不太乐观,因此迫切需要早期诊断和新的治疗策略来提高胶质瘤患者的生存率.我们前期的研究工作发现血浆miR-454-3p可能在胶质瘤预后方面有一定优势,但对于miR-454-3p在胶质瘤中的临床意义...
the effects of miR-454-3p overexpression on the proliferation of GBM cells were analyzed. LN-229 cells were transfected with control miR, miR-454-3p mimic or negative control miR-454-3p mimic, and the relative expression of miR-454-3p was verified by RT-qPCR (Fig. 2A). As was demonstra...
mir-454-3ppromotesproliferationandinducesapoptosisinhumancervicalcancer 系统标签: cervicalmircancerapoptosiscellstargeting miR-454-3ppromotesproliferationandinducesapoptosisinhumancervicalcancercellsbytargetingTRIM3YuSonga,1,QisangGuoa,1,ShujunGaoa,**,KeqinHuab,*aMedicalCenterofDiagnosisandTreatmentforCervicalDiseases...
miR-454-3p mimics (50 nM) or antagomiR-454-3p (100 nM) were transiently transfected into HAECs using Lipofectamine RNAiMAX Transfection reagent (Invitrogen; Thermo Fisher Scientific, Inc.), according to the manufacturer's protocol. The sequences are listed as follows: miR-454-3p mimic, 5'-...
The suppression by miR-454-3p on RPRD1A was found to activate Wnt/β-catenin signaling, thereby promoting metastasis. Simultaneously, three other negative regulators of the Wnt/β-catenin pathway, namely, AXIN2, dickkopf WNT signaling pathway inhibitor (DKK) 3 and secreted frizzled related ...
Linc00887 bound with miR-454-3p, and overexpression of miR-454-3p rescued linc00887-induced inhibition proliferation and invasion of HeLa cells. MiR-454-3p targeted and suppressed the expression of FRMD6, and linc00887 suppressed tumorigenesis of cervical cancer through activating the FRMD6-Hippo...
In summary, miR-454-3p and miR-374b-5p negatively regulated invasion and migration of BCa cell lines via targetting ZEB2. 展开 关键词: ZEB2 bladder cancer miR-374b-5p miR-454-3p migration DOI: 10.1042/BSR20181436 年份: 2018 收藏 引用 批量引用 报错 分享 ...
To further verify the negative regulation of miR-454-3p by HOTAIR, we silenced HOTAIR using siHOT and found that HOTAIR expression was downregulated and that miR-454-3p expression was markedly enhanced in HCS-2/8 cells (Figure 4b). In addition, miR-454-3p was downregulated in HCS-2/8 ...
(d) MiR-454-3p was significantly downregulated in chondrosarcoma tissues compared with normal cartilage tissues. The bars illustrated S.E.M. **P<0.01 by Student’s t-test. (e) The correlation between HOTAIR and miR-454-3p expression levels in 24 chondrosarcoma tissues. (f) HOTAIR and miR...
货号:chi-miR-454-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:chi-miR-454-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...