Li HT, Zhang H, Chen Y, Liu XF, Qian J. MiR-423-3p enhances cell growth through inhibition of p21Cip1/Waf1 in colorectal cancer. Cellular physiology and biochemistry. 2015; 37:1044-1054.Li HT, Zhang H, Chen Y, Liu XF, Qian J: MiR-423-3p enhances cell growth through inhibition ...
货号:cgr-miR-423-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:cgr-miR-423-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
综上所述,这些数据证实miR-101-3p和miR-423-5p在MB细胞中均发挥抗肿瘤作用,并且任一miRNA的上调均可抑制MB细胞增殖、迁移和侵袭,同时也可促进细胞凋亡。 3)单核细胞/巨噬细胞来源的外泌体miR-101-3p和miR-423-5p可转移到MB细胞中 我们发现...
为了确定含有miR-101-3p和miR-423-5p的外泌体的来源,从THP-1单核细胞培养上清中分离出外泌体,并检测miR-101-3p和miR-423-5p的表达。发现miR-101-3p和miR-423-5p在分离的外泌体中的表达高于THP-1细胞(图3B)。用转染miR-101-3p/miR-423-5p模拟物或miR-NC的THP-1细胞衍生的外泌体培养Daoy细胞,观察到...
外周血来源的外泌体可被肿瘤细胞内化(图1G,1H)。总之,这些结果表明miR-101-3p和miR-423-5p在来源于MB患者血浆的外泌体中富集,并且可以通过这些外泌体输送到肿瘤细胞。 2)MiR-101-3p和MiR-423-5p在体外MB细胞中作为肿瘤抑制因子发挥作用 我们使用CCK-8分析了miR-101-3p和miR-423-5p对MB细胞增殖能力的影响...
Moreover, miR-101-3p also targeted EZH2, a histone methyltransferase, to reinforce its tumor inhibitory effects. Using a xenograft nude mouse model of MB, we further identified that the overexpression of miR-101-3p and miR-423-5p inhibited tumorigenesis in vivo. Our findings provide novel ...
2024年10月26日,武汉大学曹正国,Huang Xin,张玉峰共同通讯在Journal of Nanobiotechnology在线发表题为“Apoptotic vesicles from macrophages exacerbate periodontal bone resorption in periodontitis via delivering miR-143-3p targeting Igfbp...
Retraction: CircSETD3 (Hsa_circ_0000567) suppresses Hepatoblastoma pathogenesis via targeting the mir-423-3p/Bcl-2-interacting mediator of cell death axisdoi:10.3389/fgene.2024.1521304CHIEF executive officersCELL deathPUBLISHED articlesHEPATOBLASTOMA
miR-423-3p was significantly associated with smoker, age, and pathologic stage of LUAD patients.#Moreover, overexpressing miR-423-3p could facilitate LUAD cell proliferation, invasion, adhesion, and epithelial-mesenchymal transition (EMT) process, while depleted miR-423-3p caused repressive influence...
In addition, ZNF674-AS1 expression is negatively correlated with miR-423-3p in NSCLC specimens. Conclusions ZNF674-AS1 suppresses NSCLC growth by downregulating miR-423-3p and inducing p21. This work suggests the therapeutic potential of ZNF674-AS1 in the treatment of NSCLC....