Glucocorticoid excess causes bone loss due to decreased bone formation and increased bone resorption; miR-433-3p is a microRNA (miRNA) that negatively regulates bone formation in male mice by targeting Runx2 as well as RNAs involved in Wnt, protein kinase A, and endogenous glucocorticoid ...
mmu-miR-433-3pmouseMIMAT0001420 过表达/干扰病毒载体种类所带的荧光基团 干扰腺相关病毒ZsGreen或GFP mmu-miR-433-3p基因腺相关病毒干扰-科维创由上海科维创生物科技有限公司 为您提供,如您想了解更多关于mmu-miR-433-3p基因腺相关病毒干扰-科维创 报价、型号、参数等信息,欢迎来电或留言咨询。
·L-1)组、奥沙利铂组、联合用药组细胞增殖抑制率、凋亡率和miR-433-3p表达显著增加(P<0.05),细胞侵袭数目、SRC蛋白表达显著减少(P<0.05);与黄芩苷300 μmol·L-1组、奥沙利铂组相比,联合用药组细胞增殖抑制率、凋亡率显著增加,细胞侵袭数目显著减少;与黄芩苷300 μmol·L-1组比较,miR-433-3p表达显著...
Taken together, these results suggest that miR-433-3p may function as a potential marker in diagnostic and therapeutic target for glioma. 展开 关键词: CREB carcinogenesis chemosensitivity glioma miR-433-3p DOI: 10.18632/oncotarget.13789 被引量: 17 ...
Glucocorticoid excess causes bone loss due to decreased bone formation and increased bone resorption; miR-433-3p is a microRNA (miRNA) that negatively regulates bone formation in male mice by targeting Runx2 as well as RNAs involved in Wnt, protein kinase A, and endogenous glucocorticoid signaling...
oar-miR-433-3p qPCR试剂盒 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产物的翻译,从而起到转录后调控靶基因的表达。 miRNAs广泛存在于动物、植物、真菌及病毒的基因组中,调控生物体生长...
miR-433-3p overexpression lentivirus; hU6-MCSCMV-EGFP was used as the vector for the NORAD and miR-433-3p knockdown lentiviruses. The NORAD knockdown plasmid, NORAD overexpression plasmid containing the wild-type binding site for miR-433-3p, NORAD overexpression plasmid containing a mutated ...
433-3p显著表达(如图E);通过斯皮尔曼相关分析,Circ-MBOAT2和miR-433-3p呈负相关(如图F);在PANC-1和SW1990细胞中,Circ-MBOAT2显著高表达,而miR-433-3p显著低表达(如图G和H);然而在这两株细胞中,通过si- Circ-MBOAT2敲减其在细胞中的表达检测miR-433-3p mRNA表达水平,发现miR-433-3p显著上升(如图I)...
Conclusion Circ-MBOAT2 modulated tumor development and glutamine catabolism by miR-433-3p/GOT1 axis in pancreatic cancer. This finding suggests that circ-MBOAT2 may be a therapeutic target for pancreatic cancer. 展开 关键词: Pancreatic cancer Circ-MBOAT2 miR-433-3p GOT1 ...
【摘要】目的 研究过表达miR-338-3p在内皮细胞系EOMA中对炎症信号通路的影响.方法 将EOMA细胞分为四组即对照组、miR-338-3p过表达组、TNF-α处理组、miR-338-3p与TNF-α共处理组.用Real time PCR检测miR-338-3p及黏附分子VCAM-1和ICAM-1mRNA表达水平,Western blot分析ERK/p38 MAPK信号通路活性.结果 与对照...