网站预测SHCBP1与miR-582-3p之间存在结合靶点;双荧光素酶报告基因实验显示miR-582-3p可与野生型SHCBP1结合,从而影响荧光素酶活性;Spearman相关曲线显示SHCBP1与miR-582-3p表达量呈负相关;敲降或过表达miR-582-3p可引起SHCBP1表达量相应改变.4,miR-582-3p可逆转SHCBP1对乳腺癌细胞的活力,增殖,迁移和侵袭能力的...
3p表达量呈负相关;敲降或过表达miR-582-3p可引起SHCBP1表达量相应改变.4,miR-582-3p可逆转SHCBP1对乳腺癌细胞的活力,增殖,迁移和侵袭能力的增强作用.5,在体内实验中,miR-582-3p过表达组肿瘤体积和重量相比对照组显著减少,且瘤体中SHCBP1表达量显著降低.结论:miR-582-3p通过靶向SHCBP1抑制乳腺癌细胞的增殖,...
miR-582-3p and miR-582-5p Suppress Prostate Cancer Metastasis to Bone by Repressing TGF-β Signaling.doi:10.1016/j.omtn.2019.01.004A number of studies... - 《Molecular Therapy Nucleic Acids》 被引量: 0发表: 2019年 MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis...
Keywords: ALG3, AML, circPTK2, miR-582-3p Read this article at ScienceOpenPublisherPubMed Review Bookmark Cite as... There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience....
miR-6775-3p在乳腺癌细胞中的表达及其对乳腺癌细胞生物学行为的影响 齐正1,薛云2,李宗良3,张小冲1,雷秋香1,张提4,景立红5,刘登湘1 1. 邢台市人民医院检验科,河北 邢台 054031 ; 2. 邢台市第三医院检验科,河北 邢台 054031 ...
There are comments on PubPeer for publication: miR-1307-3p promotes tumor growth and metastasis of hepatocellular carcinoma by repressing DAB2 interacting protein (2019)
综上,我们基于DC,对C5a相关关节炎的病理过程做出如下推理:受累的炎性关节腔内的低氧因素诱导进入炎症部位的单核细胞高表达miR-342-3p和miR-210,后二者分别通过USP13和PTPN1抑制微环境中的炎性因子GM-CSF和IL-4诱导信号通路STAT5和STAT6的活化,从而抑制单核细胞分化为成熟DC,但维持这些未成熟DC高表达C5aR1,并...
血浆miR-27b-3p、PG联合G -17在早期胃癌筛查中的应用价值 血浆m i R Ｇ２７b Ｇ３p ㊁P G 联合G Ｇ１７在早期胃癌筛查中的应用价值 樊景云１,姚㊀勇１,奉㊀镭１,黄临凌２(１．遂宁市中心医院消化中心五病区,四川遂宁６２９０００;２．广西科技大学第二附属医院乳腺外科,广西南宁５３００２１)D O I...
Analysis of lncRNA-miRNA-mRNA co-regulatory network showed that lncRNA-IκBα may target IκBα through competing binding with mir-24-3p. LncRNA-IκBα and IκBα have consistent expression patterns in MPN patients. In addition, lncRNA-IκBα has predicted binding site for mir-24-3p. ...
circ_0000285 functions as an miR-582-3p sponge to strengthen Wnt/β-catenin signaling activity, thus exacerbating NB development.doi:10.1515/med-2023-0726Jun DuYingquan ZhuoXu SunMeilan NieJiafei YangXi LuoHuajian GuOpen Medicine