miR-429-3pExosomesRac1PAHInflammationRecent studies have emphasized the critical role of Telocytes (TCs)-derived exosomes in organ tissue injury and repair. Our previous research showed a significant increase in ITGB1 within TCs. Pulmonary Arterial Hypertension (PAH) is marked by a loss of ...
近日,兰州大学第二医院王志平教授团队郜栋阳和马俊海博士分别在《Journal of Oncology》和《Int J Clin Exp Med》上报道了 Y-box 结合蛋白 1 (YB-1) 与膀胱癌的预后密切相关,且通过 miR-29b-3p-VEGFA 通路促进膀胱癌的血管...
结合内参U6进行相对定量分析.结果 miR-429,miR-127-3p及miR127-5p在SiHa细胞相对于Hela细胞表达为(0.0031±0.0002),(59.3786±3.7024)和(0.0524±0.0148),相对于C33A细胞表达为(0.0059±0.0005),(15.5625±1.2780)和(0.0334±0.0103).结论 has-miR-429,has-miR-127-3p及has-miR127-5p可能与宫颈癌的HPV感染相关....
MiR-409-3p and MiR-1896 co-operatively participate in IL-17-induced inflammatory cytokine production in astrocytes and pathogenesis of EAE mice via ... X Liu,F Zhou,Y Yang,... - 《Glia》 被引量: 0发表: 2019年 MiR-409-3p and MiR-1896 co-operatively participate in IL-17-induced inflam...
动脉粥样硬化患者血清中miR-135b-5p和miR-499a-3p的表达水平分别提高了8.77倍和1.78倍.3,miR-135b-5p和miR-499a-3p抑制共同下游靶基因MEF2C的表达:与对照组相比,升高miR-135b-5p和miR-499a-3p水平后,MEF2C的蛋白水平分别下降了33.41%和20.48%,Luciferase实验荧光强度分别下降了45.67%和26.39%,而不影响MEF2C...
Similar to SOAT1 mRNA accumulation, the gga-miR-181a-5p expression was gradually elevated during development, but the concentration of gga-miR-429-3p was in the opposite direction. Transfection with gga-miR-181a-5p or gga-miR-429-3p inhibited TGFBR1 and SOAT1 in EECs. The 3' untranslated...