miR-196b-5p Affects Macrophage Polarization and Inflammation in Endometriosisdoi:10.22034/iji.2024.102744.2794Zhe XueYuyan GuoFangyun WangQinping YangQiuhong ChenTingting LinShunhe LinIranian Journal of Immunology
本研究在体外水平探讨了miR-196b-5p在成脂分化、脂质合成和脂质分解中的功能及其作用机制。方法1.在骨髓基质细胞系ST2及间充质干细胞系C3H10T1/2中,运用实时定量PCR(qRT-PCR)技术检测miR-196b-5p在转染miR-196b-5p mimics后的变化。在两个细胞系中升高或降低miR-196b-5p水平,成脂诱导分化后用油红O染色、...
货号:ssc-miR-196b-5p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:ssc-miR-196b-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转...
EVs rich in miR-196b-5p mediate the crosstalk between PTECs and fibroblast during the development of renal fibrosis, which might be associated with STAT3/SOCO2 signaling pathway. 展开 关键词: tubulointerstitial changes fibroblast fibrosis DOI: 10.1136/bmjdrc-2019-001101 ...
In contrast, down-regulation of miR-196b-5p expression decreased cell proliferation and increased apoptosis (P < 0.05). We concluded that over-expression of miR-196b-5p may be closely associated with the risk of transformation to leukemia in MDS patients. This is a preview of subscription ...
Hsa-miR-1246, hsa-miR-320a and hsa-miR-196b-5p inhibitors can reduce the cytotoxicity of Ebola virus glycoprotein in vitro. Sci. China Life Sci. 2014, 57, 959-972. [CrossRef] [PubMed]Sheng MM, Zhong Y, Chen Y, et al. Hsa-miR-1246, hsa-miR- 320a and hsa-miR-196b-5p ...
The miR-196a-5p- and miR-196b-55p-treated cells exhibited reductions of 35% (P = 0.047) and 44% (P = 0.0063), respectively. These data suggest that miR-196a-5p and miR-196b-5p play an important role in UGT2A1 regulation within the lung and potentially other aerodigestive tract ...
与Control或mimics NC组相比,miR-196-5p mimics组的细胞增殖能力明显升高(t分别为7.97、7.85,均P<0.05,图1A);细胞侵袭数目明显增加(t分别为23.21、23.82,均P<0.05,图1B),N-cadherin蛋白表达量明显上升(t分别为17.27、17.59,均P<0.05...
前期发现miR-148a、miR-196b-5p、miR-34c可能与母猪卵泡储备激活相关，为母猪POF的候选miRNA。通过qRT-PCR、细胞培养、超表达和抑制表达、Western-blotting等技术，研究3个miRNA与卵巢功能，获得如下结果： （1）成功培养猪卵巢颗粒细胞。颗粒细胞经FSHR免疫荧光鉴定为阳性，且纯度高，培养48 h时，处于S期的细胞...