miR-196b-5p与结肠癌的发生和发展有着密切联系,高表达的miR-196b-5p被认为是预测转移性结肠癌患者接种疫苗后疗效评价的生物标志物之一[8],而且结肠癌患者血清外泌体中含有miR-196b-5p,且其表达水平与结肠癌病理过程有关[9]。...
two miRNA miR-196-b-5p (p≤ 0.05) and miR-636 (p≤ 0.01) were upregulated in OSC when compared to the controls. Three miRNAs were downregulated in OSC miR-296-5p (p≤ 0.05), miR-383-5p (p≤ 0.01), and miR-422a (p≤ 0.01) (Supplementary Figure S1B). It was noted that, co...
目的:利用TCGA和GEO数据库分析miR-193b-3p和miR-196b-5p在急性髓系白血病(AML)非M3发病机制中的作用。方法1.首先利用在线数据库GEO下载GSE10358,GSE30285,GSE37642芯片数据,利用R包获得共同差异表达的基因(DEGs),并对DEGs进行GO功能富集分析,KEGG通路富集分析和PPI蛋白质互作分2.然后利用在线数据库TCGA获得169个AML...
MiR-196b-5p mimics reversed circ_0078607 or GAS7 overexpression-mediated enhanced sensitivity. Finally, circ_0078607 improved the sensitivity of DDP in vivo. Circ_0078607 attenuates DDP resistance via miR-196b-5p/GAS7 axis, which highlights the therapeutic potential of circ_0078607 to counter DDP...
The miR-196a-5p- and miR-196b-55p-treated cells exhibited reductions of 35% (P = 0.047) and 44% (P = 0.0063), respectively. These data suggest that miR-196a-5p and miR-196b-5p play an important role in UGT2A1 regulation within the lung and potentially other aerodigestive tract ...
Furthermore, the unmethylated status of the miR-196b promoter correlated with poor disease-specific survival in OSCC patients (P=0.035). Functional analysis revealed that ectopic miR-196b expression promoted oral cancer cell migration and invasion abilities, and that silencing of miR-196b could ...
Changes and Clinical Significance of Serum miR-92a,miR-143 and miR-196b in Patients with Non-small Cell Lung Cancer 在线阅读 免费下载 引用 收藏 分享 摘要 目的分析非小细胞肺癌(NSCLC)患者血清微小核糖核酸-92a(miR-92a)、微小核糖核酸-143(miR-143)、微小核糖核酸-196b(miR-196b)变化及其临床意义...
利用胃癌细胞瞬时转染 miR-196a-5p 类似物和抑制剂来研究 miR-196a-5p 的功能,通过 TargetScan 数据库预测和双荧光素酶报告基因实验证实 miR-196a-5p 与靶基因 HOXB7 之间的关系。细胞增殖实验和单克隆形成实验检测细胞增殖能力,流式细胞...
miR-196B-5P and miR-200B-3P Are Differentially Expressed in Medulloblastomas of Adults and Children. Diagnostics 2020, 10, 265 Michela Visani 1,* , Gianluca Marucci 2,† , Dario de Biase 3,* , Felice Giangaspero 4,5 , Francesca Romana Buttarelli 6 , Alba Ariela Brandes 7, Enrico ...
miR-196b;慢病毒表达载体;载体构建; 引文网络 参考文献 引证文献 共引文献 同被引文献 二级参考文献 二级引证文献 1.Differential MiRNA expression in childhood acute lymphoblastic leukemia and association with clinical and biological features[J].Scrideli;C.A.;Yunes;J.A.;Pezuk;J.A.;Brandalise;S.R.;...