(2014). Hsa- miR-1246, hsa-miR-320a and hsa-miR-196b-5p inhibitors can reduce the cytotoxicity of Ebola virus glycoprotein in vitro. Sci. China Life Sci. 57, 959-972. doi: 10.1007/s11427-014-4742-ySheng MM, Zhong Y, Chen Y, et al. Hsa-miR-1246, hsamiR-320a and hsa-miR-...
MCE 国际站:hsa-miR-196a-5p inhibitor 产品活性:hsa-miR-196a-5p inhibitor 是一种全链经过甲氧基修饰的成熟miRNA的互补单链。miRNA inhibitor通过特异性结合成熟miRNA,阻止miRNA与其靶基因的互补配对,从而抑制miRNA的功能,可用于miRNA 功能缺失性(loss-of-function)研究。 研究领域:Epigenetics 作用靶点:MicroRNA ...
circRNA_101308在宫颈癌组织中显著下调并作为肿瘤抑制因子[18],过表达circRNA_101308能抑制宫颈癌细胞增殖、侵袭和迁移。在宫颈癌细胞中发现MiR-26a-5p、MiR-196a-5p, MiR-196b-5p、MiR-335-3p和MiR-1307-3p被circRNA_101308吸收,此研究为宫颈癌的临床治疗提供了新的方向。circ_VPRBP在宫颈癌症组织和细胞中表达...
www.nature.com/scientificreports OPEN Common SNP in hsa-miR-196a-2 increases hsa-miR-196a-5p expression and predisposes to received: 22 July 2015 idiopathic male infertility in Chineseaccepted:07December2015 Han populationPublished:25January2016 Jing Lu1, Hao Gu2,3, Qiuqin Tang4, Wei...
The results of our study demonstrate that miR-495-3p and miR-486-5p down-regulate SULT2A1 expression by binding to the 3′-untranslated region (UTR) of SULT2A1 mRNA and promoting SULT2A1 mRNA degradation. Section snippets Cell culture The HepG2 human hepatocellular carcinoma cell line was ...
Hsa-miR-182-5p在结直肠癌组织中表达的临床意义及预后分析
Silencing of miR-17-5p suppresses cell proliferation and promotes cell apoptosis by directly targeting PIK3R1 in laryngeal squamous cell carcinoma. Cancer Cell Int. 2020;20:14. 16. Luo M, Sun G, Sun JW. MiR-196b affects the progression and prognosis of human LSCC through targeting PCDH-17....
Fig. 5. The mechanism whereby exosomal miR-21 promoted osteoblast proliferation and differentiation. (A) PDCD4 was downregulated by exosomes and miR-21 mimics. (B–F) The regulation of PDCD4 expression via PDCD4-overexpression plasmids and siRNA-PDCD4, and their effects on osteoblastic proliferati...
MiR-15a-5p expression in gastric cancer tissues and cells.ACluster andBVolcano plots of the microRNA chip represent the significant differences in 81 miRNAs in gastric cancer tissues.CqRT-PCR andDagarose gel electrophoresis revealed that miR-15a-5p was expressed in GES-1 and five gastric cancer...
TPRG1-AS1 is upregulated in HNSC and promotes tumorigenesis by upregulating MYO1B through hsa-miR-363-3p sponging. It has been shown that TPRG1-AS1 serves as a potential driver of non-coding RNA to promote hepatocellular carcinoma progression, and its sponging of miR-4691-5p and miR-3659...