BMC Infectious Diseases (2024) 24:182 https://doi.org/10.1186/s12879-023-08942-1 BMC Infectious Diseases RESEARCH Open Access Hsa-miR-194-5p and hsa-miR-195-5p are down-regulated expressed in high dysplasia HPV-positive Pap smear samples compared to normal cytology HPV-positive Pap...
Results: Compared to HPV-positive cytologically normal Pap smear samples, hsa-miR-194-5p and hsa-miR-195-5p relative expression decreased significantly in HPV-positive patients with a severe dysplasia Pap smear. Kaplan鈥揗eier analysis indicated a significant association between the miR-194 decrease...
we examined the expression patterns of hsa-miR-194-5p and hsa-miR-195-5p in Pap smear samples from southeast Iranian women. We compared samples that were HPV-positive
Further hsa-miR-194-5p-regulated expression and gene-hsa-miR-194-5p interactions were evaluated by western blotting and luciferase assays, respectively. Results: We identified 40 differentially expressed microRNAs, 26 up-regulated and 14 ...
PD-L1 and PD-L2 are PD-1 ligands (PD-Ls). PD-Ls over-expression is associated with poor prognosis in hepatocellular carcinoma (HCC). However, little is kno
Hsa-mir-194-5p expression is dysregulated in multiple malignancies and plays either as a tumor-suppressive or oncogenic factor in different cancers [24]. Hsa-mir-194-5p can also interact with essential signaling pathways in CC, such as the Wnt and Hippo signaling pathways [25]. p53 family ...
Also, hsa-miR-194-5p was found to contribute to the poor prognosis of OSCC by regulating CHD4 and enhancing tumor anoikis resistance via the PI3K/AKT signaling pathway. These findings suggest that CHD4 might be a therapeutic target for the effective treatment of OSCC.Qin Li...
hsa_circ_0020377miR-194-5pOral squamous cell carcinoma (OSCC) is a common malignant tumor with high recurrence, metastasis rates, and poor prognosis. Numerous studies discover that circular RNA (circRNA) is closely associated with OSCC progression. Hsa_circ_0020377 has been aberrantly expressed in ...