Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma. Neuro-Oncology. 2014;16(11):1547–53. Article PubMed PubMed Central Google Scholar Hammouche S, et al. Long-term survival analysis of atypical meningiomas: survival rates, prognostic factors, ...
The current systematic review aimed to investigate the meningioma model types used, perform a meta-analysis on tumor take rate (TTR), and perform critical appraisal of the included studies. The study also aimed to assess reproducibility, reliability, means of validation and verification of models, ...
VASCULAR endothelial growth factorsMENINGIOMASOMATOSTATIN receptorsSKULL baseCEREBELLOPONTILE angleBackground: Meningiomas account for approximately 1/3 of primary intracranial tumours in adults, with an age-adjusted incidence rate of approximately 7 per 100,000 person-years. meningiomas comprises 37.6...
Local control and overall survival in atypical meningioma: a retrospective study. Purpose: To evaluate local control and overall survival after primary surgery for patients with atypical meningiomas. Methods and Materials: From the Depar... LK Goyal,JH Suh,DS Mohan,... - 《International Journal ...
Additionally, sulforaphane effectively slowed down NRF2 degradation rate in response to silencing of AURKA, as compared to its absence (Fig. 6F and G). Taken together, these results indicate that AURKA inhibits the proteasomal degradation of NRF2 through an interaction between NRF2 and KEAP1. ...
As such, although clinical outcomes were emphasized herein, there is much more to the complete story than survival, which can be influenced by molecular signatures of the tumor, salvage therapies, and other factors. Toxicity reductions are arguably just as important, but still suffer from the ...
This study aimed to evaluate factors affecting survival. METHODS. We performed a multi-institutional retrospective chart review study of patients with HGM (defined as grade 2 or 3 meningioma) whose tumor had undergone next-generation sequencing. Statistical testing was performed in Stata/MP version ...
Progression free survival (PFS) and overall survival (OS) analyses were performed using the Kaplan–Meier method. Risk factors for recur- rence and hazard ratios were calculated by univariate Cox regression analysis. The Chi-square test or Fisher's exact test were used to compare categorical ...
We observed a significantly worse overall survival outcome in C1 compared to C2 (P < 0.0001; hazard ratio 17.0, 95% CI 5.2–56.0) (Fig. 2g; Supplementary Table S8). The subgroups were well balanced with respect to potential confounding features such as gender, age, radiotherapy, ...
(PFS) across all molecular groups and longer overall survival in proliferative meningiomas. Dural margin treatment (Simpson grade 1/2) prolonged PFS compared to no treatment (Simpson grade 3). Molecular group classification predicted response to radiotherapy, including in the RTOG-0539 cohort. We ...