Risk factors for atypical meningioma include the male gender, previous surgeries, and a location that is not in the skull base. There is a high recurrence rate for atypical meningiomas, even following gross total resection. Increased recurrence is linked to bone involvement. Brain invasion usually ...
The most commonly used, IOMM-Lee, shows a high tumor take rate in subgroup analysis for both orthotopic models 87% (95% CI 95–98%) and heterotopic models 94% (90–96%), and it shows median survival of 10–27 days in orthotopic models, depending on the number of cells. In general...
The differences between two groups were analyzed by Student's t-test, one-way or two-way analysis of variance (ANOVA). The log-rank test was used to calculate the statistical significance of the Kaplan–Meier survival curve. P < 0.05 was considered to have statistical significance. 2.29. ...
Progression free survival of chordoid, otherwise grade 1 meningioma was comparable to non-chordoid WHO grade 1 meningioma (p = 0.75), and significantly better than chordoid WHO grade 2 meningioma (p = 0.019). Conclusion: the chordoid histology alone may not justify a universal WHO ...
(MG) for primary analysis and DKFZ methylation subclass to confirm the molecular diagnosis of meningioma).e,f, Kaplan–Meier survival curves showing PFS of meningiomas based on WHO grade (e) and MG (f).g–h, OS of meningiomas used in our study based on classification by WHO grade (g) ...
We observed a significantly worse overall survival outcome in C1 compared to C2 (P < 0.0001; hazard ratio 17.0, 95% CI 5.2–56.0) (Fig. 2g; Supplementary Table S8). The subgroups were well balanced with respect to potential confounding features such as gender, age, radiotherapy, ...
A meningioma is as serious of a condition as is any other brain tumor. However, most meningiomas are non-cancerous and tend to grow very slowly. More importantly, people diagnosed with meningioma have a high survival rate, and most meningiomas are treatable and manageable. ...
In contrast, no significant association between the DNA ploidy status of meningioma patients and their disease-free survival was found ( P = 0.1). Regarding the proliferative activity of neoplastic cells, we found that a high proportion of S-phase cells (>1.8%) was associated with a ...
Importantly, Ki-67 has been found to be more predictive of survival than expression of p53 and proliferating cell nuclear antigen (PCNA) in brain tumors [21], [22]. Previous studies have reported an association between Ki-67 index and aggressive meningioma behavior [23], [24], [25], [26...
Patients without atypical histology or behavior had a 15-year local control rate of 71%, contrasted with 54% for patients with atypical histology or behavior (p-bar = .0011). Univariate and multivariate analysis for cause-specific survival revealed that treatment group (SE vs others), histology...