L. et al. Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells. Science 351, aad5510 (2016). Article PubMed PubMed Central Google Scholar Bleriot, C. et al. Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-...
Trem2,Lpl, andCtsdexpression. Several studies in neurodegenerative diseases have reported cells expressing this signature at the scRNA level [23, 83,101,102,103]. However, Silvin et al. argued that this signature was not
人肝配蛋白A受体3(EPHA3)酶联免疫吸附测定试剂盒 别称:EPHA3, Epha3, AW492086, Cek4, ETK1, End3, Hek, Hek4, Mek4, Tyro4, EK4, ETK, EPH receptor A3, HEK, HEK4, TYRO4 Human EPHA3(Ephrin Type A Receptor 3) ELISA Kit 用途 该试剂盒用于体外定量检测Human 血清,血浆或其他生物体液中天...
Macrophages, being the cornerstone of the immune system, have adapted the ancient nutrient acquisition mechanism of phagocytosis to engulf various infectious organisms thereby helping to orchestrate an appropriate host response. Phagocytosis refers to the process of internalization and degradation of particulat...
Similarly, multiple studies from our laboratory and others have shown that GM-CSF can be used to suppress a number of different autoimmune diseases in animals including Experimental Autoimmune Thyroiditis (EAT), Experimental Autoimmune Myasthenia Gravis (EAMG), Type 1 Diabetes (T1D) and ...
Another type of macrophage proliferation can be triggered by Th2 immunity, which can be modeled in vitro by treatment of basal macrophages with interleukin-4 (IL-4) (Bosurgi et al., 2017; Jarjour et al., 2019; Jenkins et al., 2011). We therefore questioned whether efferocytosis and IL-...
10k Accesses 81 Citations 2 Altmetric Explore all metrics Abstract Background Despite improved clinical outcomes seen following antiretroviral therapy (ART), resting CD4+ T cells continue to harbor latent human immunodeficiency virus type one (HIV-1). However, such cells are not likely the solitary...
Ym1 is a secretory lectin that promotes Th2 cytokine expression [42], whereas Mrc2 is a C-type receptor for mannose that promotes remodeling of the ECM and the uptake and degradation of collagen [29]. Both Mgl1 (clec10a) and Mgl2 as markers for alternatively activated macrophages are typ...
Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat. Cell 157, 1292–1308 (2014). Article CAS PubMed PubMed Central Google Scholar Fischer, K. et al. Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose ...
wildtype SUN2 and its SA mutant in which the βTrCP-binding motif was disrupted. WT, wildtype; SA, SUN2 (S131A/S132A/S136A).fThe average size of the nucleus of THP-1-derived macrophages stably expressing the SUN2 SA mutant.e.v., empty vector; SA, SUN2 (S131A/S132A/S136A),...