The number of Tregs was significantly positively correlated with the expression levels of preoperative CEA and CA19-9.Conclusion M2-type macrophages may induce Tregs generation through activation of the TGF-尾/Smad signalling pathway, which can promote the development of colorectal cancer....
Exosomes derived from induced pluripotent stem cells suppresses M2-type macrophages during pulmonary fibrosis via miR-302a-3p/TET1 axisAuthor(s): Yan Zhou , Yuan Gao , Wei Zhang , Yingying Chen , Minglan Jin , Zehui Yang Publication date Created: October 2021 ...
145 Views 2 CrossRef citations to date 0 Altmetric ORIGINAL RESEARCH Triggering Receptor Expressed on Myeloid Cells 2 Mediates the Involvement of M2-Type Macrophages in Pulmonary Tuberculosis Infection Xiaoqian Shang, Naifeisha Maimaiti, Jiahui Fan, Liang Wang, Yuanyuan Wang, Hu Sun, ...
Form-Deprivation treatment promotes sclera M2-type macrophage polarization in FD-T eyes.The selective inhibition of M2 macrophage polarization can suppress FDM development.In the M2 macrophage and human sclera fibroblasts (HSFs) co-culture system, M2 macrophages could promote HSFs ECM remodeling.关键词...
Osimertinib resistance limits the treatment of epidermal growth factor receptor-(EGFR)-mutated non-small-cell lung carcinoma (NSCLC). The mechanisms of osimertinib resistance need to be elucidated to determine alternative treatment strategies. This study
Explore the effects of mitochondrial transplantation (MT) after cardiopulmonary resuscitation (CPR) on the polarization of microglia/macrophages (MG/MΦ) and neurological function. Seventy-five Sprague-Dawley rats were randomly divided into five groups:
6a). We observed a reduced number of macrophages recruited by tumors in miR-1246 inhibitor-treated than in CTL inhibitor-treated mice (p < 0.05,t-test). The combination of paclitaxel with miR-1246 inhibitor resulted in even fewer macrophages compared to the CTL miRNA–paclitaxel combination...
macrophagesovarian neoplasmsBreast cancer relapse is a vast clinical problem. Tumors relapsing after chemotherapy are known to develop multidrug resistance. In this paper the authors investigate the possibility of multidrug resistance cross-induced by radiotherapy. Cytotoxic assay and cell cycle analysis ...
It was confirmed by co-culture that ICC cells could polarize macrophages towards M2 type through the influence of NAT10 on CCL2 protein expression level. Through RNA-sequencing, molecular docking, and surface plasmon resonance (SPR) assays, it was confirmed that berberine (BBR) can specifically ...
Upon CCL2 or IL-6 stimulation, CD11b+ cells demonstrated a significant increase in the mannose receptor (CD206) and the CD14+/CD206+ double-positive cells, suggesting a polarization of macrophages toward the CD206+ M2-type phenotype. Caspase-8 inhibitors mimicked the cytokine-induced up-...