M2-type macrophagesPTENSpinal cord injuryMacrophages can be polarized towards either a classically activated pro-inflammatory (M1) state, or alternatively towards an activated anti-inflammatory (M2) state. M1 cells are activated by ligands of toll-like receptor (TLR) or interferon (IFN)-纬 and ...
Exosomes derived from induced pluripotent stem cells suppresses M2-type macrophages during pulmonary fibrosis via miR-302a-3p/TET1 axisAuthor(s): Yan Zhou , Yuan Gao , Wei Zhang , Yingying Chen , Minglan Jin , Zehui Yang Publication date Created: October 2021 ...
6a). We observed a reduced number of macrophages recruited by tumors in miR-1246 inhibitor-treated than in CTL inhibitor-treated mice (p < 0.05,t-test). The combination of paclitaxel with miR-1246 inhibitor resulted in even fewer macrophages compared to the CTL miRNA–paclitaxel combination...
Osimertinib resistance limits the treatment of epidermal growth factor receptor-(EGFR)-mutated non-small-cell lung carcinoma (NSCLC). The mechanisms of osimertinib resistance need to be elucidated to determine alternative treatment strategies. This study
Explore the effects of mitochondrial transplantation (MT) after cardiopulmonary resuscitation (CPR) on the polarization of microglia/macrophages (MG/MΦ) and neurological function. Seventy-five Sprague-Dawley rats were randomly divided into five groups:
RT-PCR assay showed expression of Arg-1 and FIZZ 1 mRNA were higher in M2 macrophages, and on the contrary, the expression of iNOS mRNA expression was higher in M1 macrophages. The expression of TNF-α mRNA in M1 was significantly higher than that in M2, whereas the expression of IL-10...
Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type polarization of macrophages (2015). Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type polarization of macrophages. Dis...
Introduction: Targeting innate immune checkpoints on tumor-associated macrophages (TAMs) like CD40 activation or CD47 blockade is currently tested as a pro... SS Singh,RV Sable,A Kumari,... - 《Cancer Research》 被引量: 0发表: 2022年 AntiCD206 antibodyconjugated Fe3O4based PLGA nanoparticles...
macrophagesovarian neoplasmsBreast cancer relapse is a vast clinical problem. Tumors relapsing after chemotherapy are known to develop multidrug resistance. In this paper the authors investigate the possibility of multidrug resistance cross-induced by radiotherapy. Cytotoxic assay and cell cycle analysis ...
Presence of M2-type (CD163+) macrophages exacerbated T cell immunosuppression, since frequencies of CD163+ tumor-associated macrophages were directly correlated with the frequencies of suppressed TIM-3+ PD-1+ T cells. Moreover, depletion of CD163+ macrophages significantly improved T cell ...