( 1997 ) Regulation of macrophage cytokine production by prostaglandin E 2 . Distinct roles of cyclooxygenase-1 and −2 . J. Biol. Chem. 272 : 25693 – 25699 .Williams JA, Shacter E: Regulation of macrophage cytokine production by prostaglandin E2. Distinct roles of cyclooxygenase-1 and ...
Consistently, SUN1/2 depletion in macrophages facilitates their phagocytosis, tissue infiltration, and proinflammatory cytokine production, thereby boosting the antitumor immunity in mice. Thus, our study demonstrates that, in response to inflammatory cues, SUN1/2 proteins act as mechano-regulators to ...
Stimulation of macrophage TNFalpha production by orthopaedic wear particles requires activation of the ERK1/2/Egr-1 and NF-kappaB pathways but is independent of p38 and JNK. J Cell Physiol. 2008 Dec;217(3):Beidelschies MA,Huang H,McMullen MR,et al.Stimulation of macrophage TNFalpha ...
英文名称:Elisa kit to Macrophage scavenger receptor types I and II MSR1Elisa kit to Macrophage scavenger receptor types I and II MSR1 is available 2 times 来自 Cusabio labs,中文名称:巨噬细胞清道夫受体Ⅰ型和Ⅱ型Elisa试剂盒MSR1。巨
Macrophages, i.e., pivotal immune cells, have long been enigmatic in terms of their diversity and roles during human development. Based on findings in rodents, the scientific community has gained some insights into the diversity, developm...
Cellular and Molecular Life Sciences(2024) TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury Wen-Jing Zhong Jun Zhang Yong Zhou Journal of Translational Medicine(2023) Metabolic heterogeneity of tissue-resident macrophages in homeostasis an...
The number of Mac-1 and integrin α4 was estimated to be approximately 4 × 104 cell−1and 2 × 104 cell−1, respectively (Fig. 7C and S5). This suggests that different polarization states did not significantly affect the expression of the main target receptors on the ...
TREM2 promoted glycolysis and lactylation in macrophages during wound healing. Mechanistically, TREM2 promoted macrophage glycolysis and angiogenesis in wounded skin tissues by activating the Akt/mTOR/HIF-1α signaling pathway. HIF-1α colocalized with Klac to mediate lactylation in macrophages, and...
18 Monocytes/macrophages are believed to express three integrins in the β1 family, namely, the fibronectin receptors α4/β1 and α5/β1 and the laminin receptor α6/β1. In addition, there are four members of the leukocyte-specific β2 integrin family with αL, αM, αX, or αD ...
Increasing rates of autoimmune and inflammatory disease present a burgeoning threat to human health1. This is compounded by the limited efficacy of available treatments1 and high failure rates during drug development2, highlighting an urgent need to bett