MACROPHAGE RECRUITMENT AND IL-10 INDUCTION CORRELATE WITH PROTECTION PROVIDED BY RENAL ISCHEMIC PRECONDITIONING ATTENUATES RENAL ISCHEMIA/REPERFUSION INJURYpriapismsubarachnoid hemorrhagetreatmentischemiccomplicationsphenylephrineblood pressuresickle cell diseaseThe SLIT2 receptor ROBO2 plays a key role in the ...
Total RNA was obtained from mouse macrophages J774 A.1 before or after stimulation with IL-10 (20 ng/ml). Poly(A)+RNA was isolated in both cases in order to obtain driver and tester mRNA. Subtraction suppression hybridization was performed using the PCR-select cDNA subtraction procedure...
Surface IL-10 is not unique to the 12j macrophage hybrid and may correlate with the absence of bactericidal activity in other macrophages. For instance, nonlistericidal resident and thioglycolate-elicited peritoneal exudate cells have 24 to 72% IL-10-positive macrophages. In contrast listericidal ...
These results demonstrated that NLRP3 regulates macrophage IL-10 production and contributes to the pathophysiology of Dox-induced cardiotoxicity, which is independent of IL-1尾. Our findings identify a novel role of NLRP3 and provided new insights into the mechanisms underlying Dox-induced ...
Breakdown of the epithelial barrier because of toxins or other insults leads to severe colitis. Interleukin-10 (IL-10) is a critical regulator of this, yet its cellular targets and mechanisms of action are not resolved. We address this here. Mice with a
IL-10, in addition to being a cytokine synthesis-inhibitory factor, is a cytokine that exerts multiple effects on various cell types. Recombinant human migration inhibitory factor (MIF) inhibits the migration of human monocytes as well as that of guinea pig and murine macrophages. In addition, ...
This is achieved by adding a 3 day 'maturation culture' to the initial 6-7 day culture in the presence of GM-CSF and IL-4. Macrophage-conditioned ... NR A,D Reider,MH A~,... - 《Journal of Immunological Methods》 被引量: 2176发表: 1996年 ...
Suppl Fig 3a:嗜酸性粒细胞特征标志如CLC, MS4A3, CCR3 和“Th2” 细胞因子 IL4 和IL13。 Fig 2b:中性粒细胞特征标志如HCAR3, FCGR3B (CD16b), CMTM2, PROK2 等。 Fig 6a:肠道中性粒细胞可分为3个亚群,命名N1, N2和N3, 其在不同疾病和个体丰度有所差异。相较N1和N3,N2中性粒细胞表达CCL3, LG...
Myocardial infarction is the most common cause of cardiac injury and results in acute loss of a large number of myocardial cells. Because the heart has neg... NG Frangogiannis - 《Pharmacological Research》 被引量: 1114发表: 2008年 Up-Regulation and Profibrotic Role of Osteopontin in Human Idi...
Cerebral regu- latory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10. Eur J Immunol 2015; 45: 180-191.L. Xie, G. R. Choudhury, A. Winters, S.-H. Yang, and K. Jin, "Cerebral regulatory T cells restrain microglia/macrophage- mediated inflammatory responses ...