IL-4 和 IL-13 在交替激活的巨噬细胞中诱导 c-Myc 表达(MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. Journal of Leukocyte Biology.),相反,LPS 诱导的 HIF-1α 上调与 c-Myc 下调同时发生Myc 。总体而言,在没有二次刺激的情况下,训练...
3. Murray, P.J., and Wynn, T.A. (2011). Protective and pathogenic functions of macrophage subsets.Nat. Rev. Immunol.11, 723–737. https://doi.org/10. 1038/nri3073. 4. Qiao, Y., Giannopoulou, E.G., Chan, C.H., Par...
由于IL4R、IL13RA1 和 STAT6 的表达在衰老过程中下降,且 STAT6 的表达与人类的 UBE2T 和 BRCA1 呈正相关,作者接下来探讨了通过激活 2 型 IL-4 信号通路来靶向衰老细胞(图 1A、1B)。为此,作者使用由甲状腺素结合球蛋白(TBG)启动子驱动的腺相关病毒 8(AAV8)-TBG-Il4,诱导肝细胞特异性表达,在小鼠肝脏...
Furthermore, macrophage subsets can be very heterogenous (linked to their differing cellular origins) and the relative role of these subsets in the context of M(IL activation to helminth infection is unknown. An article by Rolot et al. in this issue of the European Journal of Immunology [Eur...
羊白介素4(IL4)检测试剂盒相关产品:XY-E30436 【中文名称】大鼠碱性成纤维生长因子(bFGF)ELISA试剂盒品牌 【英文名称】Rat basic fibroblast growth factor,bFGF ELISA试剂盒多少钱 XY-E30437 【中文名称】大鼠巨噬细胞炎症蛋白5(MIP-5)ELISA试剂盒品牌 【英文名称】Rat macrophage inflammatory protein 5,MIP-5...
英文名称:ELISA Kit for Interleukin 4 (IL4) 分子式:电询 纯度:99 % 产地:中国/美国/德国 品牌:BioLegend,Cygnus,IBL,TSZ等国内外品牌 包装规格:96T/48T 货号:xyA077Bo 别名:电询 通用名:牛白介素4(IL4)检测试剂盒 英文名:ELISA Kit for Interleukin 4 (IL4) ...
we established macrophages that continuously secrete IL-4, and found that single pulmonary macrophage transplantation (PMT) had an improved therapeutic effect on mice with ALI. Mortality, lung inflammation, and tissue injury decreased in mice transplanted with IL-4-secreting macrophages. PMT has been ...
Correction to: TSPO Modulates IL-4-Induced Microglia/Macrophage M2 Polarization Via PPAR-γ PathwayThe original version of this article unfortunately contained mistakes in the Author Group section. Authors Dandan Zhou and Lei Ji were assigned to incorrect institutions....
Cytokines and Receptors in Tfh Cell Differentiation and Function Macrophage Activation Markers Microglia Activation Markers Myeloid-derived Suppressor Cells (MDSC) Receptors in the Jak/STAT Pathway Regulatory T Cells (Tregs) T Cell Cytokine Signaling ...
Here we used single-cell RNA sequencing of human and mouse non-small cell lung cancer (NSCLC) lesions, and found that in both species the type 2 cytokine interleukin-4 (IL-4) was predicted to be the primary driver of the tumour-infiltrating monocyte-derived macrophage phenotype. Using a ...