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Better knowledge of EGFR and M6PR traffic in this regard may aid in understanding the pathological processes, such as oncogenic transformations associated with these receptors. Copyright 2012 John Wiley & Sons, Ltd.doi:10.1002/cbf.2827Ee Ling Ng...
LYST also plays a role in phagolysosomal maturation by controlling toll-like receptors (TLR)3- and TLR4-induced endosomal TRIF proinflammatory signaling pathways [93]. These data demonstrate how regulatory mechanisms in membrane trafficking can directly affect specific immune receptor signaling pathways, ...
S. Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. Mol. Cell. Biol. 27, 1112–1124 (2007). Article CAS PubMed Google Scholar Rojas, R. et al. Regulation of retromer recruitment to...
AMPA receptorsPROTEOLYSISLYSOSOMESThe endoplasmic reticulum (ER) forms contacts with the lysosomal compartment, regulating lysosome positioning and motility. The movements of lysosomes are controlled by the attachment of molecular motors to their surface. However, the molecular mech...
McGourty K, Thurston TL, Matthews SA, Pinaud L, Mota LJ, Holden DW. 2012. Salmonella inhibits retrograde trafficking of mannose-6- phosphate receptors and lysosome function. Science 338:963-967. http: //dx.doi.org/10.1126/science.1227037....