NextSeq 1000 & 2000 Sequencing Systems TruSight Oncology Product Family All Popular Products Do more, faster than ever Deeper studies, more samples, more modalities. The NovaSeq X and 25B flow cell make ultra-high depth multiomics more accessible. Learn more Learn Areas of Interest Techniques...
尽管长读长测序技术很强大,但也不完美。除了需要努力产生更长、准确率更高的数据,降低成本也是一个主要目标,只有便宜了各个课题组才能够用得起,也才能推动生物学更加蓬勃发展。 Method of the Year 2022: long-read sequencing. Nat Methods 20, 1 (2023). doi.org/10.1038/s41592- ...
作为“更亲和”的测序技术，长读长测序也正在不断为方法开发和生物学研究开辟新的领域，例如机器学习等前沿技术正日益成为长读长测序数据分析工具箱的核心要素。齐碳科技是国内首家自主研发出纳米孔基因测序仪并率先开启商业化的企业，目前已有上百家机构用户使用齐碳QNome测序平台，涵盖国内领先的科研院所、高校、医院...
Nature Methods 2022年年度最佳技术——long-read sequencing 2022年2月,国际顶级期刊Nature发布了【2022年度值得关注的七大顶尖生物技术榜单】,并评述这七大顶尖生物技术有望在本年对科学研究产生重大影响,长读长测序技术赫然在榜。 4月,人类基因组测序便迎来第18座里程碑——迄今最完整的人类基因组图谱发布!其中,长...
Long-read sequencing, also known as third generation sequencing, is an emerging technique that allows for the sequencing of longer DNA segments leading to improved detection of structural variants and epigenetics. These capabilities are opening a way for better characterization of brain tumors. Here, ...
长读测序(Long-Read Sequencing,LRS),即第三代DNA测序技术,可以绘制更加完整的人类基因组图谱。下一代DNA测序是基因组革命背后的驱动力。虽然短读测序(Short-Read Sequencing,SRS)在过去占主导地位,但ARK认为,长读测序将迅速获取市场份额。 ARK认为,与短读测序相比,长读测序技术可以提供更高的准确性、更全面的变体...
Sentieon | 每周文献-Long Read Sequencing(长读长测序)-第七期,研究者通过将PacBio长读长数据进行组装后对基因组进行repeat和gene注释。然后,利用测序或者从公开发表文献中下载的棉花基因组数据进行比对、变异检测、联合基因分型对亚洲栽培棉和非洲亚种进行比较。此过
PacBio incorporated the NVIDIA A100 Tensor Core GPU into its Revio system to accelerate the speed and accuracy of long‑read sequencing, while minimizing costs.
在样本数据分析部分,研究者使用Sentieon DNAseq Haplotyper模块进行单样本突变检测,并使用Sentieon GVCFtyper进行多样本联合基因分型。 综上所述,该研究发现了目前最全面、最完整的绿孔雀基因组,它将成为未来绿孔雀生态学、进化和保护研究的宝贵资源。 长读长测序系列文章-2 ...
Long-read Oxford Nanopore sequencing has democratized microbial genome sequencing and enables the recovery of highly contiguous microbial genomes from isolates or metagenomes. However, to obtain near-finished genomes it has been necessary to include shor