RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts. Nat Rev Mol Cell Biol. 2013; 11 :699–712.Geisler S, Coller J (2013) RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts . Nat Rev Mol Cell Bio 14 : 699–712...
LongNoncoding RNAsGuide the Epigenetic Machinery and Interfere with OtherNoncoding RNAFunctions to Regulate Gene Expression 106 4.1 Paradigms of Long NoncodingRNAFunction in the Regulation of Gene Expression 106 4.1.1 Long NoncodingRNAsas Guides for the Epigenetic Machinery 108 ...
RNA-mediated symmetry breaking enables singular olfactory receptor choice Messenger RNAs transcribed from olfactory-receptor genes may have non-coding functions that include recruitment of transcriptional enhancers and inhibition of potentially thousands of competing alleles to ensure stable transcription of a...
Nuclear Enriched Abundant Transcript 1 (NEAT1) is a long non-coding RNA (lncRNA) which is a crucial structural constituent of paraspeckles and has an indispensable role in the formation of paraspeckle. Paraspeckles as nuclear sub-structures are placed in the nucleus interchromatin area and parti...
然而,lncRNA在大小上存在显著差异,==长度超过10 kb的lncRNA属于超长基因间RNA (very long intergenic RNAs, vlinc)和宏观lncRNA==。这些转录本具有一些区别于其他lncRNA的特征:它们的剪接性差或不剪接,在3 '端弱聚腺苷酸化,并且由特定的基因组位点产生。大多数vlincRNA都位于同一条或相反的链上的PCG(蛋白编码...
LncRNA (Long non-coding RNA) is a class of non-coding RNA molecules with lengths exceeding 200 nucleotides and lacking protein-coding functions.
《Long Non-Coding RNA Biology》是一本由M.R.S. Rao著的专业书籍,该书于2017年由Springer出版社出版。原著中说明了可以用于交流学习,不涉及商业用途就可以,因此不存在侵权问题。 本书是关于长非编码RNA(lncRNA)的综合性教材,涵盖了lncRNA的多个方面,包括结构、功能、调节机制、疾病相关性等等。该书共分为10章...
Long Non-Coding RNA Sequencing Introduction Long non-coding RNAs (lncRNAs) are thought to encompass nearly 30,000 different transcripts in humans, hence lncRNA transcripts account for the major part of the non-coding transcriptome. lncRNA discovery is still at an early stage and only a small pr...
名词解释长非编码 RNA(long non-coding RNA,IncRNA) 答案 长非编码RNA:是一类长度为200~100000个核苷酸的RNA分子。lncRNA由RNA聚合酶Ⅱ转录生成,经剪切加工后,形成具有类似于mRNA的结构。lncRNA有poly(A)尾和启动子,但序列中不存在可读框,不编码任何蛋白质。lncRNA具有调控的多样性,可从染色质重塑、转录调控及转...
Real-time PCR gene expression and long non-coding RNA workflow: Step 1:Isolate RNA Step 2:Design and optimize primers Step 3:Reverse transcription Step 4:Amplify cDNA Step 5:Run qPCR Step 6:Analyze Isolate RNA Isolate RNA using methods that ...