Yao, RW., Wang, Y. & Chen, LL. Cellular functions of long noncoding RNAs.Nat Cell Biol21, 542–551 (2019). https://doi.org/10.1038/s41556-019-0311-8 Download citation Received12 August 2018 Accepted11 March 2019 Published02 May 2019 ...
Based on previously published studies, in this review, we summarize the different functions of lncRNAs in sepsis-induced cellular disorders and sepsis-induced organ failure to show the potential roles of lncRNAs in the diagnosis and management of sepsis. We further depict the function of some ...
Long noncoding RNAs (lncRNAs) have been implicated in the pathogenesis of intracellular pathogens. However, the role and mechanism of the important lncRNAs in Mycobacterium tuberculosis (M.tb) infection remain largely unexplored. Recently, we found that a secreted M.tb Rv1579c (an early secreted...
Long noncoding RNAs (lncRNAs) undergo extensive alternative splicing, but little is known about isoform functions. A prior investigation of lncRNA RP11-369C8.1 reported that its splice variant TRMP suppressed p27 translation through PTBP1. Here we characterize a second major splice variant, TRMP...
long noncoding RNAs; 27.Gastrodin relieves inflammation injury induced by lipopolysaccharides in MRC‐5 cells by up‐regulation of miR‐103 机译:天麻素通过上调miR-103减轻MRC-5细胞中脂多糖诱导的炎症损伤 作者:Zhuona Xi;Yahong Qiao;Jifang Wang;Hongjian Su;Zhen Bao;Hongyan Li;Xiaoming Liao;Xiaolan...
provide valuable insights into the identification of biomarkers and the development of novel therapeutic agents. Circular RNAs (circRNAs) represent a distinct class of noncoding RNAs (ncRNAs) characterized by their covalently closed, continuous loop structures. Research has identified differentially expressed...
期刊名称:《Journal of cellular and molecular medicine.》 | 2019年第9期 关键词: cervical cancerfeedback looplong non‐coding RNAmicroRNAprogression; 15.LncRNA SNHG6 functions as a ceRNA to regulate neuronal cell apoptosis by modulating miR‐181c‐5p/BIM signalling in ischaemic stroke 机译:Ln...
BackgroundAnti-angiogenic therapy has become one of the effective treatment methods for tumors. Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis and angiogenesis in EC. However, the underlying mechanisms of lncRNA TRPM2-AS in EC are still not clear.MethodsWe scre...
Finally, endogenously expressed noncoding RNAs, including long noncoding RNAs (lncRNAs) and microRNAs (miRNAs), play critical roles in the posttranscriptional regulation of gene expression by acting as competing RNAs, although they do not directly affect chromatin structure. lncRNAs are a large group...
Novel cellular functions of well-studied miRNAs and less well-known miRNAs putatively involved in HF progression were identified. This comprehensive screening approach unveils the complimentary cellular actions of various miRNAs in different cell types involved in cardiovascular disease and opens new avenues...