Evolution and Functions of Long Noncoding RNAs LOGO EvolutionandFunctionsofLongNoncodingRNAs Reporter:EnhuiShenSupervisor:LongjiangFanDate:2014/7/02 PontingCPetal.,Cell,2009;SaltaEetal.,TheLancetNeurology,2012;MaHetal.,TheScientificWorldJournal,2012.Contents 1 23 Introduction Classification Origins 4 Func...
Long non-coding RNA overlapping with protein-coding gene (lncRNA-coding pair) is a special type of overlapping genes. Protein-coding overlapping genes have been well studied and increasing attention has been paid to lncRNAs. By studying lncRNA-coding pairs in human genome, we showed that lncRNA...
Volatile evolution of long noncoding RNA repertoires: mechanisms and biological implications. Trends Genet.: TIG 2014;30:439-52.Kapusta A, Feschotte C. Volatile evolution of long noncoding RNA repertoires: mechanisms and biological implications. Trends Genet 2014; 30:439-52; PMID:25218058; http:...
Small non-coding RNA transcriptomic profiling in adult and fetal human brain Article Open access 12 July 2024 Long non-coding RNAs: definitions, functions, challenges and recommendations Article 03 January 2023 References Birney, E. et al. Identification and analysis of functional elements in ...
Gong, J., Liu, W., Zhang, J., Miao, X. & Guo, A. Y. lncRNASNP: a database of SNPs in lncRNAs and their potential functions in human and mouse.Nucleic Acids Res.43, D181–D186 (2015). ArticleCASPubMedGoogle Scholar Wapinski, O. & Chang, H. Y. Long noncoding RNAs and ...
mRNA-like long non-coding RNAs (lncRNAs) are a significant component of mammalian transcriptomes, although most are expressed only at low levels, with high tissue-specificity and/or at specific developmental stages. Thus, in many cases lncRNA detection by RNA-sequencing (RNA-seq) is compromised ...
So did the limited diversity of proteins in phylogeny lead to the suggestion that non-coding RNA might have important regulatory functions? Yes. Since the protein-coding repertoire (notwithstanding some clade-specific innovations) has remained relatively static, the differences in developmental complexity...
TEs contain transcriptional and splicing regulatory sequences and also promote the production of non-cod- ing RNA (ncRNA), e.g., microRNA (miRNA) and long non-coding RNA (lncRNA) [15, 22, 23]. To further rep- licate in the host genome, TEs, especially LTR elements, can retain ...
The HOX gene clusters are thought to be highly conserved amongst mammals and other vertebrates, but the long non-coding RNAs have only been studied in detail in human and mouse. The sequencing of the kangaroo genome provides an opportunity to use comparative analyses to compare the HOX clusters...
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