Single-cell sequencing, as a novel bioanalysis technology, has significantly contributed to the understanding of the global cognition and dynamic changes in liver cancer. However, there is a lack of bibliometric analysis in this specific research area. Therefore, the objective of this study is to ...
Single-cell RNA sequencing (scRNA-seq) has emerged as a potent approach to exploring cancer and its microenvironment in a single-cell resolution21,22,23,24,25,26but with a deficiency in a morphological resolution for exploring solid tumors. Spatial transcriptomics (ST), a lately-developed high-...
6、对肿瘤区域的克隆型T细胞进行了分析,发现危重病人的克隆型Treg占据的比例更高,同时发现了这样一个亚群CD8+FOXP3+,分析克隆发现是,CD8+FOXP3-的细胞分化而来, Tregs and exhausted CD4 T cell clusters 共享很少,indicated the potential conversion from exhausted CD4 T cells to inducible Tregs。 最后看一下文...
Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer Multiregion sequencing is needed to better capture the heterogeneity of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). Here, the authors analyse HCC and iCCA tu...
单细胞测序显示肝癌中浸润T细胞的景观图(Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing) 科学问题: 1.在过去的十年里,免疫治疗显著的改善了癌症治疗的状况,但对于不同的肿瘤病人或肿瘤类型,它的效果是不一致的。突变数量、肿瘤浸润的淋巴细胞和药物靶点表达等若干因素,虽然与...
Although the application of single-cell multi-omics in liver cancer research has been limited thus far, a revolution of individualised care for patients with HCC will only be possible by integrating various unimodal methods into multi-omics methodologies at the single-cell resolution. In this review...
Liver cancer arises from the evolutionary selection of the dynamic tumor microenvironment (TME), in which the tumor cell generally becomes more heterogeneous; however, the mechanisms of TME-mediated transcriptional diversity of liver cancer remain unclear. Here, we assess transcriptional diversity in 15...
网络释义 1. 肝癌细胞 circulating cancer cell_翻译 ... 肺癌细胞: lung cancer cell 肝癌细胞: Liver cancer cell 癌干细胞: cancer stem cell ... www.lw23.com|基于2个网页 例句 释义: 全部,肝癌细胞 更多例句筛选 1. Objective: To study the inhibition mechanism of aloe polysaccharide(AP)on the ...
single-cell technologies and multiomics), with several liver scRNA-seq studies being published in the past 5 years [17,18,19,20,21,22,23]. Recently, several reviews have summarised the application of single-cell techniques in various types of liver diseases, especially liver cancer [24], ...
In addition, single-cell approaches are starting to dissect key cellular and molecular functions in liver cancer. In the near future, new techniques such as spatial transcriptomics and multiomic approaches will further deepen our understanding of disease pathogenesis, enabling the identification of novel...