´Receptor-ligand interactions - cell signaling, adhesion :的受体-配体相互作用的细胞信号转导,粘附受体,相互,细胞,cell,CELL,Cell,受体配体,细胞受体,cells 文档格式: .ppt 文档大小: 1.78M 文档页数: 30页 顶/踩数: 0/0 收藏人数: 0 评论次数: ...
Thus, in order to measure the interaction of a ligand with its cell surface receptor, it is essential to have a grasp of the many variables that can affect such measurements. In this chapter, we attempt to provide a suitable context in which the measurements of ligand-receptor interactions ...
The interaction of ligands with G protein-coupled receptors (GPCRs) has been traditionally studied using radiolabelled variants of receptor ligands. More r... SJ Briddon,B Kellam,SJ Hill - 《Methods in Molecular Biology》 被引量: 46发表: 2011年 Single-molecule force spectroscopy: a method for...
knowledge of the chemical natures of the ligand-receptor interactions. According to (4), the computational method is thus established for estimation of cell-cell affinity based on scRNA-seq data and ligand-receptor interactions. In practice, we used the human ligand-receptor interaction database FAN...
Cell Receptor-Ligand Interaction, Signalling, Activation and ApoptosisBackground: Rheumatoid arthritis is a chronic inflammatory condition of the joints in which the accumulation of leucocytes in the synovial membrane results in the development of inflammation, joint destruction and pain. Chemokines and ...
These datasets provide improved resolution of cell types and specific markers, including subdivision of the renal stroma and heterogeneity within the nephron progenitor population. Ligand-receptor interaction and pathway analysis reveals novel crosstalk between cellular compartments and associates new pathways ...
(receptor), protein folding, protein aggregation etc. The interactions between ligands and the hydrophobic side chains of proteins contribute significantly to the binding free energy. The hydrophobic interaction is related to binding free energy that is determined by the amount of hydrophobic surface ...
Fig. 4: Quantitative interaction analysis in vitro and in live cells reveals IL-25-induced IL-17RB–IL-17RA binding via the tip-to-tip interface. a–c, IL-17RB–IL-17RA interactions in the plasma membrane quantified by live-cell single-molecule imaging. a, Different receptor labelling sch...
receptordynamics: Each T-cell clone is found to adjust its threshold of activation, most likely by fixing different levels of signaling molecules (receptor, co-receptor, kinases, etc.). This observation implies that: (1) Fine-tuning the TCR signaling machinery during interaction with self antig...
We hypothesized that ECFC exosomes target ischemic kidneys, involving interaction between exosomal CXC chemokine receptor type 4 (CXCR4) and stromal cell-derived factor (SDF)-1α. Ischemia-reperfusion was induced in mice by bilateral renal vascular clamp, with intravenous infusion of exosomes at ...