Active sites of ligands and their receptors are made of common peptides that are also found elsewhere - Ohno - 1995 () Citation Context ...hat occur frequently in proteins, because the probability for a newly emergent receptor (or ligand) would find a useful ligand (or receptor) is ...
KEy TLR LIGANDS AND THEIR RECEPTORSLigands, T L R
We also evaluated how their expression recovers after corneal epithelium injury. We found that all ligands studied (Sema3A, Sema3F, EphrinB1, EphrinB2, Netrin-1, and Netrin-4) are abundantly expressed in both the TG and corneal epithelium. Similarly, their receptors (Neuropilin-1, Neuropilin-2...
Active sites of ligands and their receptors are made of common peptides that are also found elsewhere 喜欢 0 阅读量: 8 作者:Susumu,Ohno 摘要: The simultaneous emergence in evolution of a ligand and its receptor might have entailed their active sites being drawn from the pool of common ...
(2005). The ErbB receptors and their ligands in cancer: an overview. Curr Drug Targets 6: 243-257.Normanno N,Bianco C,Strizzi L. The ErbB receptors and their ligands in cancer:an overview[J].Current Drug Targets,2005,(03):243-257.doi:10.2174/1389450053765879....
In recent years, however, it has become obvious that subgroups of opioids and opioid receptors must be considered. One particularly interesting subgroup is represented by the endogenous morphine-like substances, the endorphins, which are peptides. It is the purpose of this communication to review ...
These ligands and their receptors constitute the endogenous cannabinoid system. The discovery of this system has important physiological, pathophysiological, pharmacological, and therapeutic implications. Already selective CB 1 - and CB 2 -receptor agonists and antagonists have been developed and two ...
Toll-Like receptors (TLRs) and their ligands. Handb. Exp. Pharmacol. 2008 : 1-20.Uematsu S, Akira S. Toll‐like receptors (TLRs) and their ligands. In: Bauer S, Hartmann G, editorler. Toll‐Like Receptors (TLRs) and Innate Immunity. 1st ed. Heidelberg: Springer‐Verlag; 2008. p. ...
EPH receptors (EPHs), together with cell-bound signalling-competent ligands (ephrins), regulate cell positioning, tissue patterning and stem cell maintenance during normal and neoplastic development. Their specialized functions are driven via the signalling of oligomeric EPH–ephrin clusters into both int...
This book summarises current studies which involve receptors and ligands in neurological disorders. The advance in the study of receptors in general enables investigators to explore the mechanism of action of psychotropic drugs and to minimise their side effects. It will lead to the study of molecul...