基因敲入(Knock-in)模型的应用: 模拟人类遗传机制,探索致病机制 示踪基因表达 进行谱系示踪,追溯细胞起源 将小鼠基因人源化,加速药物研发 将分子遗传学工具引入小鼠模型中 基因敲入模型包括: 常规基因敲入 点突变 条件性点突变 人源化 通过CRISPR基因编辑技术,构建一个基因敲入小鼠模型一般需要6-9个月。 通过...
中文名称基因敲入(KNOCK-IN)小鼠模型 中文同义词基因敲入(KNOCK-IN)小鼠模型 英文名称KNOCK-IN Mouse Model 英文同义词KNOCK-IN Mouse Model CAS号 分子式 分子量0 EINECS号 相关类别 Mol文件Mol File 结构式 基因敲入(KNOCK-IN)小鼠模型 性质 基因敲入(KNOCK-IN)小鼠模型 用途与合成方法 ...
KNOCK-IN Mouse Model 中文名: 基因敲入(KNOCK-IN)小鼠模型 中文别名: 基因敲入(KNOCK-IN)小鼠模型 CBNumber: CB05788341 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商4 基因敲入(KNOCK-IN)小鼠模型化学性质 安全信息 基因敲入(KNOCK-IN)小鼠模型性质、用途与生产工艺 ...
A knock-in mouse into which a mutant amyloid precursor protein (mutant APP) gene described in (a) or (b), below, has been introduced, said mouse being homozygous for the mutant APP gene. (a) A mutant APP gene that codes a mutant murine amyloid-&bgr; protein and comprises the amino ...
The present invention relates to transgenic animals, particularly a knock-in-mouse, as well as to a targeting vector, which is provided for the generation of an animal such as a knock-in-mouse. The present invention further relates to stem cells, preferably murine embryonic stem cells, containi...
(GOIs) and is readily adapted to generate humanized mouse models – reproducing the human expression patterns in mice.With our project strategies, we have used RMCE-based techniques (with BAC fusion and 3 targeting rounds) to achieve large-fragment knockin (LFKI) humanization and genetic ...
A tissue specific Knock-In mouse model developed by Creative Animodel, helps to insert new gene at a particular organ of the animal body using vector design and ES cell targeting technique.
“Cyagen made two reporter knock-in mice (i.e. MLC-2v-tdTomato and Nppa-tagBFP) which were used in my recent public... —— Young-Jae Nam, Vanderbilt University Medical Center "Our lab has been using Cyagen’s transient transgenic mouse embryo LacZ service to test candidate sequences fo...
knock in 美 英 na.打进 网络基因敲入;打入;基因敲入的 英汉 网络释义 na. 1. 打进,敲进,(英大学)迟到后敲门进去 例句 更多例句筛选
P.2.028 Active and passive MDMA ('ecstasy') intake induces differential transcriptional changes in the mouse brain We used a particle-based Monte Carlo simulation to dissect the regulatory mechanism of molecular translocation of CaMKII, a key regulator of neuronal synap... J M.,Orejarena,and,....